Association of longitudinal white matter degeneration and cerebrospinal fluid biomarkers of neurodegeneration, inflammation and Alzheimer's disease in late-middle …

AM Racine, AP Merluzzi, N Adluru, D Norton… - Brain imaging and …, 2019 - Springer
Alzheimer's disease (AD) is characterized by substantial neurodegeneration, including both
cortical atrophy and loss of underlying white matter fiber tracts. Understanding longitudinal …

[HTML][HTML] Cerebrospinal fluid biomarkers of neurofibrillary tangles and synaptic dysfunction are associated with longitudinal decline in white matter connectivity: a multi …

WH Kim, AM Racine, N Adluru, SJ Hwang… - NeuroImage: Clinical, 2019 - Elsevier
In addition to the development of beta amyloid plaques and neurofibrillary tangles,
Alzheimer's disease (AD) involves the loss of connecting structures including degeneration …

Conditional recurrent flow: conditional generation of longitudinal samples with applications to neuroimaging

SJ Hwang, Z Tao, WH Kim… - Proceedings of the IEEE …, 2019 - openaccess.thecvf.com
We develop a conditional generative model for longitudinal image datasets based on
sequential invertible neural networks. Longitudinal image acquisitions are common in …

Associations between positron emission tomography amyloid pathology and diffusion tensor imaging brain connectivity in pre-clinical Alzheimer's disease

SJ Hwang, N Adluru, WH Kim, SC Johnson… - Brain …, 2019 - liebertpub.com
Characterizing Alzheimer's disease (AD) at pre-clinical stages is crucial for initiating early
treatment strategies. It is widely accepted that amyloid accumulation is a primary …