Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer

J Bellier, MJ Nokin, E Lardé, P Karoyan… - Diabetes research and …, 2019 - Elsevier
Diabetes is one of the most frequent diseases throughout the world and its incidence is
predicted to exponentially progress in the future. This metabolic disorder is associated with …

SIRT1-dependent upregulation of antiglycative defense in HUVECs is essential for resveratrol protection against high glucose stress

SJ Santini, V Cordone, M Mijit, V Bignotti, P Aimola… - Antioxidants, 2019 - mdpi.com
Uncontrolled accumulation of methylglyoxal (MG) and reactive oxygen species (ROS)
occurs in hyperglycemia-induced endothelial dysfunction associated with diabetes …

2-Iodo-4′-methoxychalcone attenuates methylglyoxal-induced neurotoxicity by activation of GLP-1 receptor and enhancement of neurotrophic signal, antioxidant …

YT Tseng, YH Tsai, F Fülöp, FR Chang, YC Lo - Molecules, 2019 - mdpi.com
Methylglyoxal (MG) acts as a reactive precursor of advanced glycation end products (AGEs).
This compound is often connected with pathologies such as diabetes, neurodegenerative …

Evidence that hydrogen peroxide, a component of oxidative stress, induces high-anxiety-related behaviour in mice

J Bouayed, R Soulimani - Behavioural brain research, 2019 - Elsevier
The link between oxidative stress and high-anxiety-related behaviour is uncontested; but the
cause-effect relationship has yet to be completely elucidated. Here, the behavioural effects …

2′ O-galloylhyperin attenuates LPS-induced acute lung injury via up-regulation antioxidation and inhibition of inflammatory responses in vivo

SD Zhang, P Wang, J Zhang, W Wang, LP Yao… - Chemico-biological …, 2019 - Elsevier
Abstract 2′ single bondO-galloylhyperin, an active flavonol glycoside compound with
remarkable anti-immune activity, was isolated from Pyrola [P. incarnata Fisch.]. However, the …

Protective effects of anthocyanin against apoptosis and oxidative stress induced by arsanilic acid in DF-1 cells

N Xie, N Geng, D Zhou, Y Xu, K Liu, Y Liu… - Molecular biology reports, 2019 - Springer
Anthocyanin is a natural plant pigment that acts as an antioxidant and scavenges free
radicals. This study aimed to investigate the potential protective role of nightshade …

Antiglycative activity and RAGE expression in Rett syndrome

V Cordone, A Pecorelli, M Benedusi, S Santini Jr… - Cells, 2019 - mdpi.com
Rett syndrome (RTT) is a human neurodevelopmental disorder, whose pathogenesis has
been linked to both oxidative stress and subclinical inflammatory status (OxInflammation) …

[PDF][PDF] SIRT1-Dependent Upregulation of Antiglycative Defense in HUVECs Is Essential for Resveratrol Protection against High Glucose Stress

V Dolo, S Falone, F Amicarelli - researchgate.net
Uncontrolled accumulation of methylglyoxal (MG) and reactive oxygen species (ROS)
occurs in hyperglycemia-induced endothelial dysfunction associated with diabetes …

Gıda tatlandırıcıları glikasyon ürünleri uyarımlı amiloid oluşumu üzerine fosfodiesteraz 1b geni ekspresyon seviyelerinin araştırılması

A KÜÇÜKGÜL, A KÜTÜKOĞLU - Avrasya Sağlık Bilimleri Dergisi, 2019 - dergipark.org.tr
In this study, it was aimed to investigate the effects of methylglyoxal, metabolic end product
of high-fructose diets, on in vitro beta amyloid formation, secondary messenger molecule …