Currently used bioproduction systems for chemicals and fuels are primarily based on sugar-
containing substrates. They have inherent limitations regarding substrate sustainability and …

Highlights•Methanol is a cheap substrate for large-scale bioproduction of fuels and
chemicals.•Native methylotrophs are difficult to engineer and don't produce metabolites at …

Background Methanol has attracted increased attention as a non-food alternative carbon
source to sugar for biological production of chemicals and fuels. Moreover, the high degree …

Methanol, commercially generated from methane, is a renewable chemical feedstock that is
highly soluble, relatively inexpensive, and easy to handle. The concept of native …

Background Crude glycerol coming from biodiesel production is an attractive carbon source
for biological production of chemicals. The major impurity in preparations of crude glycerol is …

Abstract One-carbon (C1) feedstocks can provide a vital link between cheap and
sustainable abiotic resources and microbial bioproduction. Soluble C1 substrates, methanol …

Methane is a promising next-generation carbon feedstock for industrial biotechnology
because it is inexpensive and abundant carbon. Biological conversion of methane to …

Microbial fermentation for chemical production is becoming more broadly adopted as an
alternative to petrochemical refining. Fermentation typically relies on sugar as a feedstock …

Methanol is one of the most promising renewable feedstocks for the replacement of fossil
fuels in the 21st century, due to its high energy density and the prospect of million-ton scale …

Cupriavidus necator H16 is a chemolithoautotrophic Gram-negative bacterium that belongs
to the class of-proteobacteria. In recent years, it has attracted the biotechnological attention …