From SARS to MERS, thrusting coronaviruses into the spotlight

Z Song, Y Xu, L Bao, L Zhang, P Yu, Y Qu, H Zhu… - viruses, 2019 - mdpi.com
Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory
pathogens to humans. However, two outbreaks of severe respiratory tract infection, caused …

The middle east respiratory syndrome (MERS)

EI Azhar, DSC Hui, ZA Memish, C Drosten… - Infectious Disease …, 2019 - id.theclinics.com
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a new zoonotic human
viral pathogen endemic to the Middle East. 1–3 It was identified in 2012 in a lung sample of …

Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks

DS Hui, BK Chow, T Lo, OTY Tsang… - European …, 2019 - Eur Respiratory Soc
Background High-flow nasal cannula (HFNC) is an emerging therapy for respiratory failure
but the extent of exhaled air dispersion during treatment is unknown. We examined exhaled …

High-throughput screening and identification of potent broad-spectrum inhibitors of coronaviruses

L Shen, J Niu, C Wang, B Huang, W Wang… - Journal of …, 2019 - Am Soc Microbiol
Coronaviruses (CoVs) act as cross-species viruses and have the potential to spread rapidly
into new host species and cause epidemic diseases. Despite the severe public health threat …

Antiviral peptides as promising therapeutic drugs

LCP Vilas Boas, ML Campos, RLA Berlanda… - Cellular and Molecular …, 2019 - Springer
While scientific advances have led to large-scale production and widespread distribution of
vaccines and antiviral drugs, viruses still remain a major cause of human diseases today …

[PDF][PDF] Clinical management of severe acute respiratory infection when Middle East respiratory syndrome coronavirus (MERS-CoV) infection is suspected: interim …

World Health Organization - 2019 - apps.who.int
The first edition of this document was published in 2013 and was revised in 2015. The
current version is aligned with other WHO documents on case definitions and laboratory …

Epitope‐based peptide vaccine design and target site depiction against Middle East Respiratory Syndrome Coronavirus: an immune-informatics study

M Tahir ul Qamar, S Saleem, UA Ashfaq, A Bari… - Journal of translational …, 2019 - Springer
Abstract Background Middle East Respiratory Syndrome Coronavirus (MERS-COV) is the
main cause of lung and kidney infections in developing countries such as Saudi Arabia and …

Urogenital tuberculosis—epidemiology, pathogenesis and clinical features

A Muneer, B Macrae, S Krishnamoorthy… - Nature Reviews …, 2019 - nature.com
Tuberculosis (TB) is the most common cause of death from infectious disease worldwide. A
substantial proportion of patients presenting with extrapulmonary TB have urogenital TB (UG …

Immune responses to Middle East respiratory syndrome coronavirus during the acute and convalescent phases of human infection

HS Shin, Y Kim, G Kim, JY Lee, I Jeong… - Clinical Infectious …, 2019 - academic.oup.com
Background An understanding of immune responses against the Middle East respiratory
syndrome (MERS) is important for the development of treatments and preventive measures …

Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study

FY Alqahtani, FS Aleanizy, RAEH Mohamed… - Epidemiology & …, 2019 - cambridge.org
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a life-threatening
respiratory disease with a high case fatality rate; however, its risk factors remain unclear. We …