The kidney is frequently involved in adverse effects caused by exposure to foreign
compounds, including drugs. An early prediction of those effects is crucial for allowing novel …

There are now many reports of human kidney organoids generated via the directed
differentiation of human pluripotent stem cells (PSCs) based on an existing understanding of …

Organ constructs are organ-like structures grown in vitro or in vivo that harbor the
components, architecture, and function of in vivo organs, in part or in toto. The convergence …

Nephrotic syndrome is classically categorized by the histopathology with examples
including focal segmental glomerulosclerosis (FSGS) and minimal change disease …

Nephron progenitors (NPs) and nephrogenesis have been extensively studied in mice and
humans and have provided insights into the mechanisms of renal development, disease and …

Cellular crosstalk is essential for proper organogenesis. Although originally assumed to be
simple conduits for blood, endothelial cells (ECs) actively coordinate organ development …