No support for historical candidate gene or candidate gene-by-interaction hypotheses for major depression across multiple large samples

R Border, EC Johnson, LM Evans… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Interest in candidate gene and candidate gene-by-environment interaction
hypotheses regarding major depressive disorder remains strong despite controversy …

Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigm

PR Albert, B Le François, F Vahid-Ansari - Journal of psychiatry and …, 2019 - jpn.ca
Major depression and anxiety are highly prevalent and involve chronic dysregulation of
serotonin, but they remain poorly understood. Here, we review novel transcriptional (genetic …

Developmental timing of polyvictimization: Continuity, change, and association with adverse outcomes in adolescence

CB Dierkhising, JD Ford, C Branson, DJ Grasso… - Child Abuse & …, 2019 - Elsevier
Children who experience polyvictimization (ie, exposure to multiple and varied traumatic
stressors) are at heightened risk for psychopathology. While polyvictims generally have …

[PDF][PDF] Ungdoms erfaringer med vold og overgrep i oppveksten

GS Hafstad, EM Augusti - En nasjonal undersøkelse av norsk ungdom i …, 2019 - nkvts.no
Det er en prioritert samfunnsoppgave å beskytte barn mot vold og overgrep. Likevel tyder
tidligere undersøkelser på at altfor mange barn og unge opplever vold, seksuelle overgrep …

Molecular and genetic bases of mammalian maternal behavior

AS Fleming, GW Kraemer - Gender and the Genome, 2019 - journals.sagepub.com
New mammalian mothers undergo an increase in their maternal responsiveness with the
birth of their infants. Associated with changes in responsiveness are how attracted mothers …

5-HTTLPR–brain-derived neurotrophic factor (BDNF) gene interactions and early adverse life events effect on impulsivity in suicide attempters

L Jiménez-Treviño, PA Saiz… - The World Journal of …, 2019 - Taylor & Francis
Objectives: An expanding body of research suggests that childhood adverse experiences
can lead to different negative health outcomes, including attempted suicide. Serotonergic …

HPA-axis multilocus genetic variation moderates associations between environmental stress and depressive symptoms among adolescents

LR Starr, M Huang - Development and psychopathology, 2019 - cambridge.org
Research suggests that genetic variants linked to hypothalamic-pituitary-adrenal (HPA)-axis
functioning moderate the association between environmental stressors and depression, but …

[HTML][HTML] No interaction between childhood maltreatment and serotonin transporter gene in recurrent major depressive disorder: a clinical sample

G Özçürümez, HT Yurdakul, Y Terzi… - Archives of …, 2019 - ncbi.nlm.nih.gov
Methods: Participants included a well-characterized clinical sample of 70 recurrent MDD
cases and 67 never psychiatrically ill controls, aged 18 years or over. Socio-demographic …

Expression of Tumor Necrosis Factor-Alpha in a Chick Model of Stress Vulnerable, Treatment–Resistant Depression

MK Jourdan - 2019 - egrove.olemiss.edu
An increasing body of literature suggests a Major Depressive Disorder subpopulation,
Treatment Resistant Depression (TRD), is associated with an increased immune response …

Psychosomatic Medicine and Consultation-Liaison Psychiatry in the United States

H Leigh - … Medicine and Consultation-Liaison Psychiatry: Theory …, 2019 - Springer
Psychosomatic medicine in the United States is usually traced to Franz Alexander who
utilized psychoanalytic methods on patients with physical diseases and proposed that …