Changing concepts in presurgical assessment for epilepsy surgery

M Zijlmans, W Zweiphenning, N van Klink - Nature Reviews Neurology, 2019 - nature.com
Candidates for epilepsy surgery must undergo presurgical evaluation to establish whether
and how surgical treatment can stop seizures without causing neurological deficits. Various …

Optimization of surgical intervention outside the epileptogenic zone in the Virtual Epileptic Patient (VEP)

S An, F Bartolomei, M Guye, V Jirsa - PLoS computational biology, 2019 - journals.plos.org
Studies to improve the efficacy of epilepsy surgery have focused on better refining the
localization of the epileptogenic zone (EZ) with the aim of effectively resecting it. However, in …

A comparison of evoked and non-evoked functional networks

J Hebbink, D van Blooijs, G Huiskamp, FSS Leijten… - Brain topography, 2019 - Springer
The growing interest in brain networks to study the brain's function in cognition and diseases
has produced an increase in methods to extract these networks. Typically, each method …

Background EEG connectivity captures the time-course of epileptogenesis in a mouse model of epilepsy

P Słowiński, L Sheybani, CM Michel, MP Richardson… - eneuro, 2019 - eneuro.org
Large-scale brain networks are increasingly recognized as important for the generation of
seizures in epilepsy. However, how a network evolves from a healthy state through the …

The role that choice of model plays in predictions for epilepsy surgery

L Junges, MA Lopes, JR Terry, M Goodfellow - Scientific reports, 2019 - nature.com
Mathematical modelling has been widely used to predict the effects of perturbations to brain
networks. An important example is epilepsy surgery, where the perturbation in question is …

Personalised network modelling in epilepsy

Y Wang, GM Schroeder, N Sinha, PN Taylor - arXiv preprint arXiv …, 2019 - arxiv.org
Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and
network abnormalities have been associated with epilepsy, and the exact processes …

Guiding the neurosurgeon in resective epilepsy surgery

D Groothuysen - 2019 - essay.utwente.nl
Surgical treatment of focal epilepsy sometimes necessitates localization of the epileptigenic
tissue by way of invasive electrocorticography (EcoG) measurements to measure the seizure …