HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a …

K Ahmed, JM Baeten, M Beksinska, LG Bekker… - The Lancet, 2019 - thelancet.com
Background Observational and laboratory studies suggest that some hormonal
contraceptive methods, particularly intramuscular depot medroxyprogesterone acetate …

Hormonal contraceptives and the acquisition of sexually transmitted infections: an updated systematic review

KJ McCarthy, EL Gollub, L Ralph… - Sexually transmitted …, 2019 - journals.lww.com
Background Evidence suggests that some forms of hormonal contraception (HC) increase
women's risk of non-human immunodeficiency virus sexually transmitted infections (STIs) …

Mucosal immunity in HIV/SIV infection: T cells, B cells and beyond

BL Shacklett - Current immunology reviews, 2019 - ingentaconnect.com
As our understanding of mucosal immunity increases, it is becoming clear that the host
response to HIV-1 is more complex and nuanced than originally believed. The mucosal …

Defining characteristics of genital health in South African adolescent girls and young women at high risk for HIV infection

S Dabee, SL Barnabas, KS Lennard, SZ Jaumdally… - PLoS …, 2019 - journals.plos.org
The genital tract of African women has been shown to differ from what is currently accepted
as 'normal', defined by a pH≤ 4.5 and lactobacilli-dominated microbiota. Adolescent girls …

Protective effect of probiotic bacteria and estrogen in preventing HIV-1-mediated impairment of epithelial barrier integrity in female genital tract

S Dizzell, A Nazli, G Reid, C Kaushic - Cells, 2019 - mdpi.com
Approximately 40% of global HIV-1 transmission occurs in the female genital tract (FGT)
through heterosexual transmission. Epithelial cells lining the FGT provide the first barrier to …

Medroxyprogesterone acetate decreases Th1, Th17, and increases Th22 responses via AHR signaling which could affect susceptibility to infections and inflammatory …

MP Piccinni, L Lombardelli, F Logiodice… - Frontiers in …, 2019 - frontiersin.org
A synthetic progestin, medroxyprogesterone acetate (MPA), was used in a novel study to
determine progestin effects on human purified macrophages and Th1, Th2, Th17, Th22 …

Differential effects of depot medroxyprogesterone acetate administration on vaginal microbiome in Hispanic White and Black women

L Yang, Y Hao, J Hu, D Kelly, H Li… - Emerging microbes & …, 2019 - Taylor & Francis
The use of depot medroxyprogesterone acetate (DMPA), a 3-monthly injectable hormonal
contraceptive, is associated with an increased risk of HIV acquisition possibly through …

Increased Cervical CD4+CCR5+ T Cells Among Kenyan Sex Working Women Using Depot Medroxyprogesterone Acetate

J Lajoie, A Tjernlund, K Omollo, G Edfeldt… - AIDS research and …, 2019 - liebertpub.com
Depot medroxyprogesterone acetate (DMPA) is the most common hormonal contraceptive
used by women in sub-Saharan Africa, however, it has been epidemiologically associated …

Acquisition of sexually transmitted infections among women using a variety of contraceptive options: a prospective study among high‐risk African women

FM Kiweewa, E Brown, A Mishra, G Nair… - Journal of the …, 2019 - Wiley Online Library
Abstract Introduction In many African settings, women concurrently face substantial risk of
human immunodeficiency virus type 1 (HIV‐1) infection, sexually transmitted infections (STI …

[HTML][HTML] Pharmacokinetic, biologic and epidemiologic differences in MPA-and NET-based progestin-only injectable contraceptives relative to the potential impact on …

R Heffron, SL Achilles, LJ Dorflinger, JP Hapgood… - Contraception, 2019 - Elsevier
Access to safe and effective contraceptive choices is a reproductive right and contributes
tremendously to improvements in maternal and child health. Progestin-only injectables …