[HTML][HTML] Sarcopenia associated with chemotherapy and targeted agents for cancer therapy

MP Davis, R Panikkar - Annals of palliative medicine, 2019 - apm.amegroups.org
Clinicians often believe that cachexia is caused by cancer and anorexia as a toxicity of
chemotherapy or targeted anti-cancer agents. It is now recognized that chemotherapy and …

Sarcopenia & aging in cancer

GR Williams, HN Rier, A McDonald… - Journal of geriatric …, 2019 - Elsevier
Loss of skeletal muscle mass and strength is apparent as early as the 4th decade of life and
progresses linearly with increasing age [1, 2]. The term sarcopenia, first introduced by Irwin …

[HTML][HTML] Impact of sarcopenia in patients with advanced non–small cell lung cancer treated with PD-1 inhibitors: A preliminary retrospective study

T Shiroyama, I Nagatomo, S Koyama, H Hirata… - Scientific reports, 2019 - nature.com
The aim of this study was to investigate the clinical impact of sarcopenia on the efficacy of
programmed death (PD)-1 inhibitors. We retrospectively reviewed the medical records of all …

Preoperative low skeletal muscle mass as a risk factor for pharyngocutaneous fistula and decreased overall survival in patients undergoing total laryngectomy

SI Bril, TF Pezier, BM Tijink, LM Janssen… - Head & …, 2019 - Wiley Online Library
Background Low skeletal muscle mass (SMM) is associated with postoperative
complications, prolonged hospital stay, and short overall survival (OS) in surgical oncology …

Muscoloskeletal aging, sarcopenia and cancer

G Colloca, B Di Capua, A Bellieni, M Cesari… - Journal of geriatric …, 2019 - Elsevier
In the context of the management of the elderly patient with cancer, currently, a key topic
may be expressed by sarcopenia. Sarcopenia in its various definitions and ambiguities in …

[HTML][HTML] Interobserver agreement of skeletal muscle mass measurement on head and neck CT imaging at the level of the third cervical vertebra

SI Bril, AW Wendrich, JE Swartz, I Wegner… - European Archives of …, 2019 - Springer
Objectives Skeletal muscle mass (SMM) is most often assessed in cancer patients on
abdominal computed tomography (CT) imaging at the level of the third lumbar vertebra (L3) …

Sarcopenia, a strong determinant for prolonged feeding tube dependency after chemoradiotherapy for head and neck cancer

RT Karsten, A Al‐Mamgani, SI Bril, S Tjon‐A‐Joe… - Head & …, 2019 - Wiley Online Library
Background Sarcopenia might be a relevant lead for optimization of the condition of patients
with head and neck cancer (HNC) before chemoradiotherapy (CRT) to prevent long‐term …

Clinical and biological characterization of skeletal muscle tissue biopsies of surgical cancer patients

A Anoveros‐Barrera, AS Bhullar… - Journal of cachexia …, 2019 - Wiley Online Library
Background Researchers increasingly use intraoperative muscle biopsy to investigate
mechanisms of skeletal muscle atrophy in patients with cancer. Muscles have been …

Association of muscle mass with survival after radical prostatectomy in patients with prostate cancer

S Pak, SY Park, TJ Shin, D You, IG Jeong… - Journal of …, 2019 - journals.lww.com
Purpose: Although muscle mass has been associated with survival in patients with various
types of solid tumors, the relationship between muscle mass and survival in patients with …

Arrdc2 and Arrdc3 elicit divergent changes in gene expression in skeletal muscle following anabolic and catabolic stimuli

BS Gordon, ML Rossetti… - Physiological …, 2019 - journals.physiology.org
Skeletal muscle is a highly plastic organ regulating various processes in the body. As such,
loss of skeletal muscle underlies the increased morbidity and mortality risk that is associated …