Drosophila as a Genetic Model for Hematopoiesis

U Banerjee, JR Girard, LM Goins, CM Spratford - Genetics, 2019 - academic.oup.com
In this FlyBook chapter, we present a survey of the current literature on the development of
the hematopoietic system in Drosophila. The Drosophila blood system consists entirely of …

Transcription factors that govern development and disease: an achilles heel in cancer

D Huilgol, P Venkataramani, S Nandi, S Bhattacharjee - Genes, 2019 - mdpi.com
Development requires the careful orchestration of several biological events in order to
create any structure and, eventually, to build an entire organism. On the other hand, the fate …

[HTML][HTML] Endocardially derived macrophages are essential for valvular remodeling

A Shigeta, V Huang, J Zuo, R Besada, Y Nakashima… - Developmental cell, 2019 - cell.com
During mammalian embryogenesis, de novo hematopoiesis occurs transiently in multiple
anatomical sites including the yolk sac, dorsal aorta, and heart tube. A long-unanswered …

Model system identification of novel congenital heart disease gene candidates: focus on RPL13

AM Schroeder, M Allahyari, G Vogler… - Human molecular …, 2019 - academic.oup.com
Genetics is a significant factor contributing to congenital heart disease (CHD), but our
understanding of the genetic players and networks involved in CHD pathogenesis is limited …

MYOD and HAND transcription factors have conserved recognition sites in mTOR promoter: insights from in silico analysis

A Awasthi, V Nain, R Puria - Interdisciplinary Sciences: Computational Life …, 2019 - Springer
Abstract mTOR regulates multiple cellular processes that are critical for proper maintenance
of cell growth and development. However, mechanisms and factors responsible for …