Physical activity can treat and prevent depressive symptoms, but its antidepressant
mechanisms are yet to be established. In this review, we comprehensively assess key …

Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

Major depressive disorder (MDD) is common and disabling, but its neuropathophysiology
remains unclear. Most studies of functional brain networks in MDD have had limited …

As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …

Youth (including both childhood and adolescence) is a period when the brain undergoes
dramatic remodeling and is also a time when neuropsychiatric conditions often emerge …

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Altered structural brain asymmetry in autism spectrum disorder (ASD) has been reported.
However, findings have been inconsistent, likely due to limited sample sizes. Here we …

New approaches to the neurobiology of posttraumatic stress disorder (PTSD) are needed to
address the reported crisis in PTSD drug development. These new approaches may require …

Background Childhood maltreatment is a leading environmental risk factor for an
unfavourable course of disease in major depressive disorder. Both maltreatment and major …

Today, we see a growing concern for the quality of life of nonhuman animals and an
accompanying call for viable means of assessing how well animals thrive. Past research …