Shared and distinct functions of type I and type III interferons

HM Lazear, JW Schoggins, MS Diamond - Immunity, 2019 - cell.com
Type I interferons (IFNs)(IFN-α, IFN-β) and type III IFNs (IFN-λ) share many properties,
including induction by viral infection, activation of shared signaling pathways, and …

Type I interferons in autoimmune disease

MK Crow, M Olferiev, KA Kirou - Annual Review of Pathology …, 2019 - annualreviews.org
Type I interferons, which make up the first cytokine family to be described and are the
essential mediators of antivirus host defense, have emerged as central elements in the …

Porcine interferon complex and co-evolution with increasing viral pressure after domestication

J Jennings, Y Sang - Viruses, 2019 - mdpi.com
Consisting of nearly 60 functional genes, porcine interferon (IFN)-complex represents an
evolutionary surge of IFN evolution in domestic ungulate species. To compare with humans …

[HTML][HTML] The Comparison Between the Mutated HuIFN-β 27-101 and the Wild Type Interferon β: the Comprehensive In Silico Study to Evaluate the Effect of Mutations …

SS Balkhi, Z Hojati - Advanced Pharmaceutical Bulletin, 2019 - ncbi.nlm.nih.gov
Purpose: Interferon beta (IFN-β) is used to combat multiple sclerosis (MS) disease. Creating
R27T and V101F mutations (mHuIFN-β-27 and mHuIFN-β-101) is one of the tasks …