Networks have been recently proposed for modeling dynamics in several kinds of
psychological phenomena, such as personality and psychopathology. In this work, we …

The advent of large-scale microbiome studies affords newfound analytical opportunities to
understand how these communities of microbes operate and relate to their environment …

Ferroptosis, a non-apoptotic form of programmed cell death, is triggered by oxidative stress
in cancer, heat stress in plants, and hemorrhagic stroke. A homeostatic transcriptional …

Oxytocin is a neuropeptide involved in animal and human reproductive and social behavior.
Three oxytocin signaling genes have been frequently implicated in human social behavior …

Autism spectrum disorder (ASD) is thought to emerge during early cortical development.
However, the exact developmental stages and associated molecular networks that prime …

Tissue-specific regulatory regions harbor substantial genetic risk for disease. Because brain
development is a critical epoch for neuropsychiatric disease susceptibility, we characterized …

Excitatory neurons are preferentially impaired in early Alzheimer's disease but the pathways
contributing to their relative vulnerability remain largely unknown. Here we report that …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

Macrophages are well recognized for their dual roles in orchestrating inflammatory
responses and regulating tissue repair. In almost all acutely inflamed tissues, 2 main …

Assigning functions to the vast array of proteins present in eukaryotic cells remains
challenging. To identify relationships between proteins, and thereby enable functional …