Cutaneous wound healing is the process by which skin repairs itself. It is generally accepted
that cutaneous wound healing can be divided into 4 phases: haemostasis, inflammation …

Shikonin is the major bioactive component extracted from the roots of Lithospermum
erythrorhizon which is also known as “Zicao” in Traditional Chinese Medicine (TCM). Recent …

Phytochemicals gained considerable interest during the past years as source to develop
new treatment options for chemoprevention and cancer therapy. Motivated by the fact that a …

Skin is the largest organ of the human body. Being the interface between the body and the
outer environment, makes it susceptible to physical injury. To maintain life, nature has …

Acetaminophen (APAP) overdose causes acute liver injury and leads to fatal liver damage.
However, the therapies are quite limited. Shikonin is a natural product with antioxidant and …

Shikonin is a natural compound isolated from herbs and traditional medicines that have
been used in a number of countries to treat various illnesses including inflammation, virus …

Cancer is a leading cause of morbidity and mortality worldwide. Apoptosis is a process of
programmed cell death and it plays a vital role in human development and tissue …

Candidiasis is often associated with the formation of biofilms. Candida albicans biofilms are
inherently resistant to many clinical antifungal agents and have increasingly been found to …

Shikonin, a naphthoquinone derivative isolated from the root of Lithospermum erythrorhizon,
exhibits broad-spectrum antitumor activity via different molecular mechanisms. In this study …

Lithospermum officinale was used traditionally as a remedy in diseases of the urogenital
tract and as a spasmolytic, antidiarrhoeal, diuretic and lithotriptic, anti-gout, antitoxic …