FMS-like tyrosine kinase 3/FLT3: from basic science to clinical implications

JU Kazi, L Rönnstrand - Physiological reviews, 2019 - journals.physiology.org
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost
exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces …

Src-Family Kinases Impact Prognosis and Targeted Therapy in Flt3-ITD+ Acute Myeloid Leukemia

RK Patel - 2019 - search.proquest.com
Acute myelogenous leukemia (AML) is a disease characterized by undifferentiated bone-
marrow progenitor cells dominating the bone marrow. Currently the five-year survival rate for …