Antioxidant, anti-inflammatory and anticancer potential of natural bioactive compounds from seaweeds

R Sakthivel, KP Devi - Studies in natural products chemistry, 2019 - Elsevier
The term cancer refers to a group of diseases which results in altered expression of cellular
growth controls thus leading to uncontrolled proliferation of cells, metastasis and death of …

Visible‐Light‐Mediated Synthesis of β‐Chloro Ketones from Aryl Cyclopropanes

D Petzold, P Singh, F Almqvist… - Angewandte Chemie …, 2019 - Wiley Online Library
We report the visible‐light‐mediated synthesis of β‐chloro ketones from aryl cyclopropanes,
oxygen, hydrochloric acid, and nitric acid. The operationally simple and catalyst‐free method …

Discovery of Novel N-Isoxazolinylphenyltriazinones as Promising Protoporphyrinogen IX Oxidase Inhibitors

DW Wang, RB Zhang, SY Yu, L Liang… - Journal of agricultural …, 2019 - ACS Publications
Protoporphyrinogen oxidase (PPO, EC 1.3. 3.4) is a promising target for herbicide discovery.
Search for new compounds with novel chemotypes is a key objective for agrochemists …

Visible‐Light‐Induced Radical Di‐and Trifluoromethylation of β, γ‐Unsaturated Oximes: Synthesis of Di‐and Trifluoromethylated Isoxazolines

M Zhu, W Fun, W Guo, Y Tian, Z Wang… - European Journal of …, 2019 - Wiley Online Library
The visible‐light‐promoted difluoromethylation and trifluoromethylation/cyclization of β, γ‐
unsaturated oximes has been successfully accomplished with fluorinated sulfones as the …

A three-component approach to isoxazolines and isoxazoles under metal-free conditions

D Wang, F Zhang, F Xiao, GJ Deng - Organic & Biomolecular …, 2019 - pubs.rsc.org
A 1, 3-dipolar cycloaddition of 2-methylquinoline, tert-butyl nitrite (TBN) and alkynes or
alkenes for the synthesis of biheteroaryls containing both isoxazoline/isoxazole and …

Synthesis of isoxazolines by the electrophilic chalcogenation of β, γ-unsaturated oximes: fishing novel anti-inflammatory agents

EF Lopes, F Penteado, S Thurow, M Pinz… - The Journal of …, 2019 - ACS Publications
Herein, we describe a new strategy to prepare chalcogen-functionalized isoxazolines. The
strategy involves the reaction of β, γ-unsaturated oximes with electrophilic selenium and …

Synthesis of Isoxazolines from Nitroalkanes via a [4+1]‐Annulation Strategy

PY Ushakov, EA Khatuntseva… - Advanced Synthesis …, 2019 - Wiley Online Library
A novel access to isoxazolines was developed using the [4+ 1]‐annulation of α‐keto‐
stabilized sulfur ylides with N, N‐bis (siloxy) enamines derived from aliphatic nitro …

Enantioselective 5-exo-Fluorocyclization of Ene-Oximes

T Rouno, T Niwa, K Nishibashi, N Yamamoto, H Egami… - Molecules, 2019 - mdpi.com
The enantioselective 5-exo-fluorocyclization of ene-oxime compounds was demonstrated
under phase-transfer catalysis. Although deprotonative fluorinations competed, the chemical …

A chiral-at-metal asymmetric catalyzed vinylogous Michael addition of ortho-methyl aromatic nitro compounds for isoxazole derivative synthesis

SW Li, Y Du, Q Kang - Organic Chemistry Frontiers, 2019 - pubs.rsc.org
ortho-Alkyl aromatic nitro compounds as vinylogous nucleophiles in catalytic asymmetric
synthesis have rarely been reported. Herein an asymmetric vinylogous Michael addition of 5 …

Synthesis and biological evaluation of marine alkaloid-oriented β-carboline analogues

T Xu, L Shi, Y Zhang, K Wang, Z Yang, S Ke - European Journal of …, 2019 - Elsevier
Pityriacitrin is a marine alkaloid with typical β-carboline scaffold, and which has been proven
to exhibit diverse biological functions. During the course of our research for highly active …