Antioxidant effects of curcumin in models of neurodegeneration, aging, oxidative and nitrosative stress: A review

S Abrahams, WL Haylett, G Johnson, JA Carr… - Neuroscience, 2019 - Elsevier
The global burden of neurodegenerative disorders has increased substantially over the past
2 decades due to rising rates of population aging. Although neurodegenerative disorders …

[HTML][HTML] Curcumin, hormesis and the nervous system

M Concetta Scuto, C Mancuso, B Tomasello… - Nutrients, 2019 - mdpi.com
Curcumin is a polyphenol compound extracted from the rhizome of Curcuma longa Linn
(family Zingiberaceae) commonly used as a spice to color and flavor food. Several …

[HTML][HTML] Dietary polyphenols: A multifactorial strategy to target Alzheimer's disease

S Dhakal, N Kushairi, CW Phan, B Adhikari… - International journal of …, 2019 - mdpi.com
Ageing is an inevitable fundamental process for people and is their greatest risk factor for
neurodegenerative disease. The ageing processes bring changes in cells that can drive the …

[HTML][HTML] The autophagy signaling pathway: a potential multifunctional therapeutic target of curcumin in neurological and neuromuscular diseases

L Perrone, T Squillaro, F Napolitano, C Terracciano… - Nutrients, 2019 - mdpi.com
Autophagy is the major intracellular machinery for degrading proteins, lipids,
polysaccharides, and organelles. This cellular process is essential for the maintenance of …

[HTML][HTML] Recent advances in nanoencapsulation systems using PLGA of bioactive phenolics for protection against chronic diseases

R Abdul Rahim, PA Jayusman, N Muhammad… - International journal of …, 2019 - mdpi.com
Plant-derived polyphenolic compounds have gained widespread recognition as remarkable
nutraceuticals for the prevention and treatment of various disorders, such as cardiovascular …

The effects of flavonoids on human first trimester trophoblast spheroidal stem cell self-renewal, invasion and JNK/p38 MAPK activation: Understanding the …

VJ Ebegboni, RM Balahmar, JM Dickenson… - Biochemical …, 2019 - Elsevier
Adequate invasion and complete remodelling of the maternal spiral arteries by the invading
extravillous trophoblasts are the major determinants of a successful pregnancy. Increase in …

Coadministration with tea polyphenols enhances the neuroprotective effect of defatted walnut meal hydrolysate against scopolamine-induced learning and memory …

J Sheng, X Yang, Q Liu, H Luo, X Yin… - Journal of agricultural …, 2019 - ACS Publications
The present study aimed to investigate the combined effects of defatted walnut meal
hydrolysate (DWMH) and tea polyphenols (TP) on learning improvement and to explain …

[HTML][HTML] Neuroprotective Potential of Secondary Metabolites from Melicope lunu-ankenda (Rutaceae)

Z Abdulwanis Mohamed, E Mohamed Eliaser… - Molecules, 2019 - mdpi.com
Plant natural compounds have great potential as alternative medicines for preventing and
treating diseases. Melicope lunu-ankenda is one Melicope species (family Rutaceae), which …

[HTML][HTML] Senescence phenomena and metabolic alteration in mesenchymal stromal cells from a mouse model of rett syndrome

T Squillaro, N Alessio, S Capasso… - International Journal of …, 2019 - mdpi.com
Chromatin modifiers play a crucial role in maintaining cell identity through modulation of
gene expression patterns. Their deregulation can have profound effects on cell fate and …

Bound polyphenol extracted from jujube pulp triggers mitochondria-mediated apoptosis and cell cycle arrest of HepG2 cell in vitro and in vivo

S Shan, Y Xie, H Zhao, J Niu, S Zhang, X Zhang… - Journal of functional …, 2019 - Elsevier
Chinese jujube which contains many nutrients, contributes to a healthy diet. Jujube pulp
extracts are rich in polyphenol compounds exhibiting admirable pharmacological activities …