The regulatory role of Toll-like receptors after ischemic stroke: neurosteroids as TLR modulators with the focus on TLR2/4

S Tajalli-Nezhad, M Karimian, C Beyer… - Cellular and Molecular …, 2019 - Springer
Ischemic stroke is the most common cerebrovascular disease and considered as a
worldwide leading cause of death. After cerebral ischemia, different pathophysiological …

Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells

Z Zhou, C Bian, Z Luo, C Guille, E Ogunrinde, J Wu… - Scientific reports, 2019 - nature.com
Progesterone plays a protective role in preventing inflammation and preterm delivery during
pregnancy. However, the mechanism involved is unknown. Microbial product translocation …

Peripheral blood neuroendocrine hormones are associated with clinical indices of sport-related concussion

AP Di Battista, SG Rhind, N Churchill, D Richards… - Scientific reports, 2019 - nature.com
The purpose of this study was to evaluate the relationship between neuroendocrine
hormones and clinical recovery following sport-related concussion (SRC). Ninety-five …

Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampus

T Ghadiri, G Vakilzadeh, V Hajali, F Khodagholi - Neuroscience Letters, 2019 - Elsevier
Female sex hormone, progesterone, in addition to seizure modifying activity is also known
as a potential protective agent against various brain injury conditions. Considering the …

Experimental traumatic brain injury results in estrous cycle disruption, neurobehavioral deficits, and impaired GSK3β/β-catenin signaling in female rats

AM Fortress, P Avcu, AK Wagner, CE Dixon… - Experimental …, 2019 - Elsevier
An estimated 2.8 million traumatic brain injuries (TBI) occur within the United States each
year. Approximately 40% of new TBI cases are female, however few studies have …

Anti‐allodynic and anti‐inflammatory effects of 17α‐hydroxyprogesterone caproate in oxaliplatin‐induced peripheral neuropathy

CA Miguel, MC Raggio, MJ Villar… - Journal of the …, 2019 - Wiley Online Library
Chemotherapy‐induced peripheral neuropathy is a disabling condition induced by several
frequently used chemotherapeutic drugs including the front‐line agent oxaliplatin (OXA) …

Biological sex/gender and biopsychosocial determinants of traumatic brain injury recovery trajectories

JP Niemeier - Current Physical Medicine and Rehabilitation Reports, 2019 - Springer
Abstract Purpose of Review The goals of the report are to integrate recent and key
foundational gender-and sex-related, post-traumatic brain injury (TBI) literature across …

Estetrol and its effects on the damaged brain

E Tskitishvili, JM Foidart - Sex Steroids' Effects on Brain, Heart and Vessels …, 2019 - Springer
Estrogens play an important role not only in the reproductive system but in the central
nervous system as well. Major events of ontogenesis that occur earlier in pregnancy are …

Effects of progesterone at the enteric level in a mouse model of Parkinson's disease

H Jarras - 2019 - library-archives.canada.ca
Parkinson's disease (PD) is the second most common neurodegenerative disease in the
world. It is characterized by motor symptoms caused by the loss of dopaminergic neurons in …

Cognitive effects of hormone replacement therapy in menopausal women

Ž Kovačič - 2019 - repozitorij.unizg.hr
Sažetak INTRODUCTION: Hormone replacement therapy (HRT) is prescribed to women for
the treatment of postmenopausal symptoms; however, there remains doubt about what kind …