Therapeutic potential and biological applications of cordycepin and metabolic mechanisms in cordycepin-producing fungi

P Qin, XK Li, H Yang, ZY Wang, DX Lu - Molecules, 2019 - mdpi.com
Cordycepin (3′-deoxyadenosine), a cytotoxic nucleoside analogue found in Cordyceps
militaris, has attracted much attention due to its therapeutic potential and biological value …

Molecular mechanisms of action of tocotrienols in cancer: Recent trends and advancements

V Aggarwal, D Kashyap, K Sak, HS Tuli, A Jain… - International journal of …, 2019 - mdpi.com
Tocotrienols, found in several natural sources such as rice bran, annatto seeds, and palm oil
have been reported to exert various beneficial health promoting properties especially …

Bioactive metabolites of Ganoderma lucidum: Factors, mechanism and broad spectrum therapeutic potential

C Sharma, N Bhardwaj, A Sharma, HS Tuli… - Journal of herbal …, 2019 - Elsevier
Background The global interest in edible medicinal herbs for healthcare has significantly
increased during the last few years. Ganoderma lucidum is a medicinal mushroom which is …

Nutritional Mushroom Treatment in Meniere's Disease with Coriolus versicolor: A Rationale for Therapeutic Intervention in Neuroinflammation and …

M Scuto, P Di Mauro, ML Ontario, C Amato… - International Journal of …, 2019 - mdpi.com
Meniere's disease (MD) represents a clinical syndrome characterized by episodes of
spontaneous vertigo, associated with fluctuating, low to medium frequencies sensorineural …

Antimicrobial effect and proposed action mechanism of cordycepin against Escherichia coli and Bacillus subtilis

Q Jiang, Z Lou, H Wang, C Chen - journal of microbiology, 2019 - Springer
The detailed antibacterial mechanism of cordycepin efficacy against food-borne germs
remains ambiguous. In this study, the antibacterial activity and action mechanism of …

Cordycepin mitigates MPTP-induced Parkinson's disease through inhibiting TLR/NF-κB signaling pathway

C Cheng, X Zhu - Life sciences, 2019 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease with movement disorder. PD is
characterized by the loss of dopaminergic (DA) neurons in the substantia nigra. Cordycepin …

Role of reactive oxygen species in cancer progression

D Kashyap, HS Tuli, K Sak, VK Garg, N Goel… - Current Pharmacology …, 2019 - Springer
Abstract Purpose of Review Although there are significant improvements in diagnosis and
therapeutics tools, cancer remained a major cause of deaths in developing and developed …

Secondary metabolites (SMs) of Isaria cicadae and Isaria tenuipes

X Zhang, Q Hu, Q Weng - RSC advances, 2019 - pubs.rsc.org
Both Isaria cicadae and Isaria tenuipes are important entomopathogenic fungi used in
health foods and traditional herbal medicines in East Asia. However, the safety concerns for …

Green synthesis of gold nanoparticles using a Cordyceps militaris extract and their antiproliferative effect in liver cancer cells (HepG2)

Y Ji, Y Cao, Y Song - Artificial cells, nanomedicine, and …, 2019 - Taylor & Francis
Hepatocellular carcinoma is the most common liver cancer among different types of cancers.
Cordyceps Militaris mushroom species traditionally used as an alternative medicine in china …

Cordycepin exerts neuroprotective effects via an anti-apoptotic mechanism based on the mitochondrial pathway in a rotenone-induced parkinsonism rat model

X Jiang, PC Tang, Q Chen, X Zhang… - CNS & Neurological …, 2019 - ingentaconnect.com
Background: Cordycepin (Cor), one of the major bioactive components of the traditional
Chinese medicine Cordyceps militaris, has been used in clinical practice for several years …