Exploring the “multiple-hit hypothesis” of neurodegenerative disease: bacterial infection comes up to bat
KL Patrick, SL Bell, CG Weindel… - Frontiers in Cellular and …, 2019 - frontiersin.org
Despite major strides in personalized genomics, it remains poorly understood why
neurodegenerative diseases occur in only a fraction of individuals with a genetic …
neurodegenerative diseases occur in only a fraction of individuals with a genetic …
Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra
DX Ji, LH Yamashiro, KJ Chen, N Mukaida… - Nature …, 2019 - nature.com
Abstract The bacterium Mycobacterium tuberculosis (Mtb) causes tuberculosis and is
responsible for more human mortality than any other single pathogen. Progression to active …
responsible for more human mortality than any other single pathogen. Progression to active …
Changes in inflammatory protein and lipid mediator profiles persist after antitubercular treatment of pulmonary and extrapulmonary tuberculosis: A prospective cohort …
CL Vinhaes, D Oliveira-de-Souza, PS Silveira-Mattos… - Cytokine, 2019 - Elsevier
Background The identification of meaningful biomarkers of tuberculosis (TB) has potential to
improve diagnosis, disease staging and prediction of treatment outcomes. It has been …
improve diagnosis, disease staging and prediction of treatment outcomes. It has been …
An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans
Monocyte counts are increased during human tuberculosis (TB) but it has not been
determined whether Mycobacterium tuberculosis (Mtb) directly regulates myeloid …
determined whether Mycobacterium tuberculosis (Mtb) directly regulates myeloid …
Different signaling pathways define different interferon-stimulated gene expression during mycobacteria infection in macrophages
X Zhou, J Yang, Z Zhang, L Zhang, B Zhu, L Lie… - International Journal of …, 2019 - mdpi.com
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) represents one of the
greatest threats to human health., Interferons (IFNs) in combination with the first-line of anti …
greatest threats to human health., Interferons (IFNs) in combination with the first-line of anti …
Co-infection with TB and HIV: converging epidemics, clinical challenges, and microbial synergy
MB Huante, RJ Nusbaum, JJ Endsley - Tuberculosis host-pathogen …, 2019 - Springer
Human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (Mtb) are the two
leading causes of infectious disease-related death today. An estimated 2.6 million people …
leading causes of infectious disease-related death today. An estimated 2.6 million people …
Type I interferon induced by DNA of nontypeable Haemophilus influenza modulates inflammatory cytokine profile to promote susceptibility to this bacterium
S Yang, Y Yin, W Xu, X Zhang, Y Gao, H Liao… - International …, 2019 - Elsevier
Type I interferon (IFN) is indispensable for antiviral immunity, but its role in bacterial
infections is controversial and not fully described. Nontypeable Haemophilus influenzae …
infections is controversial and not fully described. Nontypeable Haemophilus influenzae …
Application of IR spectra of two successive isotope labeled residues to the evaluation of dihedral angles of polyproline II structure
D Miyata, H Hiramatsu, T Nakabayashi - Chemical Physics Letters, 2019 - Elsevier
The method to evaluate the dihedral angles of a polypeptide using IR absorption
spectroscopy was applied to a polyproline type II (PPII) structure. We have prepared 1 …
spectroscopy was applied to a polyproline type II (PPII) structure. We have prepared 1 …
An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans
Monocyte counts are increased during human tuberculosis (TB) but it has not been
determined whether Mycobacterium tuberculosis (Mtb) directly regulates myeloid …
determined whether Mycobacterium tuberculosis (Mtb) directly regulates myeloid …
[图书][B] Genetics and Mechanisms of Host Resistance against Mycobacterium tuberculosis: a Study in Mice
DX Ji - 2019 - escholarship.org
Mycobacterium tuberculosis (Mtb) infections in humans result in highly diverse outcomes
ranging from asymptomatic lung granulomas to lethal disseminated disease. Active TB …
ranging from asymptomatic lung granulomas to lethal disseminated disease. Active TB …