Managing antiphospholipid syndrome in pregnancy

K Schreiber, BJ Hunt - Thrombosis research, 2019 - Elsevier
Antiphospholipid syndrome (APS) is an autoimmune disease characterised by the presence
of antiphospholipid antibodies (aPL). The antibodies currently included in the classification …

Everything the clinician needs to know about evidence-based anticoagulation in pregnancy

LJJ Scheres, IM Bistervels, S Middeldorp - Blood reviews, 2019 - Elsevier
Pregnancy is a hemostatic challenge: women are prone to thromboembolism during their
pregnancy and at the same time, especially during delivery, there is substantial risk of …

Aspirin or heparin or both in the treatment of recurrent spontaneous abortion in women with antiphospholipid antibody syndrome: a meta-analysis of randomized …

C Lu, Y Liu, HL Jiang - The Journal of Maternal-Fetal & Neonatal …, 2019 - Taylor & Francis
Objective: This study was designed to evaluate the efficacy of aspirin or heparin or both in
the treatment for recurrent spontaneous abortion (RSA) in women with antiphospholipid …

High risk of adverse pregnancy outcomes in women with a persistent lupus anticoagulant

J Gebhart, F Posch, S Koder, P Quehenberger… - Blood …, 2019 - ashpublications.org
Lupus anticoagulant (LA) has been associated with pregnancy complications and
pregnancy loss. Identification of predictive factors could aid in deciding on therapeutic …

What's new in obstetric antiphospholipid syndrome

DW Branch - Hematology 2014, the American Society of …, 2019 - ashpublications.org
Antiphospholipid syndrome (APS) is a rare systemic autoimmune disease, the obstetric
features of which include recurrent early miscarriage, fetal death at or beyond 10 weeks of …

Management of pregnant women with antiphospholipid antibodies

A Ruffatti, M Favaro, A Calligaro… - Expert review of …, 2019 - Taylor & Francis
Introduction: Important advancements in pregnancy outcome have been reported in women
with antiphospholipid antibodies (aPL), despite the fact that the treatment of aPL related …

Outcomes in prevention and management of miscarriage trials: a systematic review

PP Smith, RK Dhillon‐Smith, E O'toole… - … Journal of Obstetrics …, 2019 - Wiley Online Library
Background There is a substantial body of research evaluating ways to prevent and manage
miscarriage, but all studies do not report on the same outcomes. Objective To review …

Heparin prevents oxidative stress-induced apoptosis in human decidualized endometrial stromal cells

S Tamaru, T Kajihara, Y Mizuno, N Takano… - Medical Molecular …, 2019 - Springer
Clinical trials have shown that administering heparin during the luteal phase has beneficial
effects on implantation and live birth rates. Heparin exerts direct effects on decidual human …

Timing of initiation of low-molecular-weight heparin administration in pregnant women with antiphospholipid syndrome: a randomized clinical trial of efficacy and …

MI Eid, MS Abdelhafez, W El-Refaie… - … Journal of Women's …, 2019 - Taylor & Francis
Objective We aimed to evaluate the effect of different timing of initiation of low-molecular-
weight heparin (LMWH) administration on the pregnancy outcomes in women with …

Low molecular weight heparin monotherapy for recurrent abortion with antiphospholipid system: a protocol of a systematic review

L Ni, X Sun, D Zhao, Z Zhu - Medicine, 2019 - journals.lww.com
Background: Previous clinical studies reported low molecular weight heparin (LMWH)
monotherpay has been utilized for the treatment of recurrent abortion (RCA) with …