Up until the mid 2000s, the capacity to generate every cell of an organism was exclusive to
embryonic stem cells. In 2006, researchers Takahashi and Yamanaka developed an …

More than a decade ago, a pioneering study reported generation of induced Pluripotent
Stem Cells (iPSCs) by ectopic expression of a cocktail of reprogramming factors in …

Embryonic stem cells (ESCs) are immortal stem cells that own multi-lineage differentiation
potential. ESCs are commonly derived from the inner cell mass (ICM) of pre-implantation …

Induced pluripotent stem cells (iPSCs) are adult somatic cells genetically reprogrammed to
an embryonic stem cell‐like state. Notwithstanding their autologous origin and their potential …

Activin receptor‑like kinases (ALKs), members of the type I activin receptor family, belong to
the serine/threonine kinase receptors of the transforming growth factor‑β (TGF‑β) …

The ability to control the transition from an undifferentiated stem cell to a specific cell fate is
one of the key techniques that are required for the application of interventional technologies …

Use of stem cells in regenerative medicine holds great promise in treating people suffering
from various otherwise incurable ailments. Direct conversion of somatic cells to other …

The term episomal induced pluripotent stem cells (EiPSCs) refers to somatic cells that are
reprogrammed into induced pluripotent stem cells (iPSCs) using non-integrative episomal …

Induced pluripotent stem (iPS) cells hold great promise for regenerative medicine and the
treatment of various diseases. Before proceeding to clinical trials, it is important to test the …

Understanding essential signaling network requirements and making appropriate
adjustments in culture conditions are crucial if porcine pluripotent stem cells (PSC) are to …