Biomarkers of acute and chronic kidney disease

WR Zhang, CR Parikh - Annual review of physiology, 2019 - annualreviews.org
The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

[HTML][HTML] Renal phosphate handling and inherited disorders of phosphate reabsorption: an update

CA Wagner, I Rubio-Aliaga, N Hernando - Pediatric Nephrology, 2019 - Springer
Renal phosphate handling critically determines plasma phosphate and whole body
phosphate levels. Filtered phosphate is mostly reabsorbed by Na+-dependent phosphate …

[HTML][HTML] Clinical aspects of the phosphate transporters NaPi-IIa and NaPi-IIb: mutations and disease associations

E Lederer, CA Wagner - Pflügers Archiv-European Journal of Physiology, 2019 - Springer
The Na+-dependent phosphate transporter NaPi-IIa (SLC34A1) is mostly expressed in
kidney, whereas NaPi-IIb (SLC34A2) has a wider tissue distribution with prominent …

A journey from microenvironment to macroenvironment: the role of metaflammation and epigenetic changes in cardiorenal disease

M Kanbay, A Yerlikaya, AA Sag, A Ortiz… - Clinical kidney …, 2019 - academic.oup.com
Chronic non-communicable diseases have become a pandemic public problem in the 21st
century, causing enormous burden on the economy, health and quality of life of societies …

The kidney transcriptome, from single cells to whole organs and back

S Huang, X Sheng, K Susztak - Current opinion in nephrology and …, 2019 - journals.lww.com
The kidney transcriptome, from single cells to whole organs... : Current Opinion in Nephrology
and Hypertension The kidney transcriptome, from single cells to whole organs and back : Current …

Decoding the genetic determinants of gene regulation in the kidney

V Nair, M Kretzler - Kidney international, 2019 - kidney-international.org
Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of
prebiotics. Nat Rev Gastroenterol Hepatol. 2017; 14: 491-502. 6. Cani PD, Lecourt E, Dewulf …

Integrative Omics for Identifying Dysfunctional Pathways in CKD

A Tin, ME Grams - Kidney International Reports, 2019 - kireports.org
The mechanisms underlying chronic kidney disease (CKD) remain poorly understood, and
treatments to prevent or forestall CKD progression are limited. Precision medicine aims to …