An overview of positive cultures and clinical outcomes in septic patients: a sub-analysis of the Prehospital Antibiotics Against Sepsis (PHANTASi) trial
RS Nannan Panday, EMJ Lammers, N Alam… - Critical Care, 2019 - Springer
Background Sepsis remains one of the most important causes of morbidity and mortality
worldwide. In approximately 30–50% of cases of suspected sepsis, no pathogen is isolated …
worldwide. In approximately 30–50% of cases of suspected sepsis, no pathogen is isolated …
Acute noncardiac organ failure in acute myocardial infarction with cardiogenic shock
S Vallabhajosyula, SM Dunlay, A Prasad… - Journal of the American …, 2019 - jacc.org
Background: There are limited data on acute noncardiac multiorgan failure in cardiogenic
shock complicating acute myocardial infarction (AMI-CS). Objectives: The authors sought to …
shock complicating acute myocardial infarction (AMI-CS). Objectives: The authors sought to …
Acute respiratory failure and mechanical ventilation in cardiogenic shock complicating acute myocardial infarction in the USA, 2000–2014
S Vallabhajosyula, K Kashani, SM Dunlay… - Annals of intensive …, 2019 - Springer
Background There are limited epidemiological data on acute respiratory failure (ARF) in
cardiogenic shock complicating acute myocardial infarction (AMI-CS). This study sought to …
cardiogenic shock complicating acute myocardial infarction (AMI-CS). This study sought to …
Phosphodiesterase-4 inhibition reduces ECLS-induced vascular permeability and improves microcirculation in a rodent model of extracorporeal resuscitation
J Wollborn, S Siemering, C Steiger… - American Journal …, 2019 - journals.physiology.org
Extracorporeal circulation can be accompanied by increased vascular permeability leading
to pathological fluid balance and organ dysfunction. The second messenger cAMP is …
to pathological fluid balance and organ dysfunction. The second messenger cAMP is …
Oncologists' and intensivists' attitudes toward the care of critically ill patients with cancer
AP Nassar Jr, ALA Dettino… - Journal of intensive …, 2019 - journals.sagepub.com
Background: Patients with cancer represent an important proportion of intensive care unit
(ICU) admissions. Oncologists and intensivists have distinct knowledge backgrounds, and …
(ICU) admissions. Oncologists and intensivists have distinct knowledge backgrounds, and …
Prevalence of organ failure and mortality among patients in the emergency department: a population-based cohort study
PB Pedersen, DP Henriksen, M Brabrand… - BMJ open, 2019 - bmjopen.bmj.com
Objectives The aim was to describe population-based incidence and emergency department-
based prevalence and 1-year all-cause mortality of patients with new organ failure present …
based prevalence and 1-year all-cause mortality of patients with new organ failure present …
Early prediction of treatment failure in severe community-acquired pneumonia: The PRoFeSs score
JM Pereira, O Laszczyńska, A Azevedo, C Basílio… - Journal of critical …, 2019 - Elsevier
Purpose To identify a single/panel of biomarkers and to provide a point score that, after 48 h
of treatment, could early predict treatment failure at fifth day of Intensive Care Unit (ICU) stay …
of treatment, could early predict treatment failure at fifth day of Intensive Care Unit (ICU) stay …
Epigenetics mechanisms in multiorgan dysfunction syndrome
E Crimi, S Cirri, G Benincasa, C Napoli - Anesthesia & Analgesia, 2019 - journals.lww.com
Epigenetic mechanisms including deoxyribonucleic acid (DNA) methylation, histone
modifications (eg, histone acetylation), and microribonucleic acids (miRNAs) have gained …
modifications (eg, histone acetylation), and microribonucleic acids (miRNAs) have gained …
Association of extracerebral organ failure with 1-year survival and healthcare-associated costs after cardiac arrest: an observational database study
PT Pekkarinen, M Bäcklund, I Efendijev, R Raj… - Critical Care, 2019 - Springer
Background Organ dysfunction is common after cardiac arrest and associated with worse
short-term outcome, but its impact on long-term outcome and treatment costs is unknown …
short-term outcome, but its impact on long-term outcome and treatment costs is unknown …
Predictive value of the kinetics of procalcitonin and C-reactive protein for early clinical stability in patients with bloodstream infections due to Gram-negative bacteria
B Gutiérrez-Gutiérrez, I Morales, S Pérez-Galera… - … and Infectious Disease, 2019 - Elsevier
Objective To investigate whether the magnitude of the change in procalcitonin (PCT) and C-
reactive protein (CRP) levels between day 1 and day 2 after the blood culture date is …
reactive protein (CRP) levels between day 1 and day 2 after the blood culture date is …