Mycobacterium tuberculosis (Mtb) senses and adapts to acidic host environments during the
course of pathogenesis. Mutants defective in acidic pH-dependent adaptations are often …

Mycofactocin is a member of the rapidly growing class of ribosomally synthesized and post-
translationally modified peptide (RiPP) natural products. Although the mycofactocin …

The phenotypic adjustments of Mycobacterium tuberculosis are commonly inferred from the
analysis of transcript abundance. While mechanisms of transcriptional regulation have been …

The success of Mycobacterium tuberculosis (MTB) stems from its ability to remain hidden
from the immune system within macrophages. Here, we report a new technology (Path‐seq) …

Here, we determined the relative importance of different transcriptional mechanisms in the
genome-reduced bacterium Mycoplasma pneumoniae, by employing an array of …

Mycobacterium tuberculosis spontaneously grows at the air-medium interface, forming
pellicle biofilms, which harbor more drug-tolerant persisters than planktonic cultures. The …

The capacity of Mycobacterium tuberculosis (Mtb) to sense, respond and adapt to a variable
and hostile environment within the host makes it one of the most successful human …

Mycobacterial σB belongs to the group II family of sigma factors, which are widely
considered to transcribe genes required for stationary-phase survival and the response to …

Progress against tuberculosis (TB) requires faster-acting drugs. Mycobacterium tuberculosis
(Mtb) is the leading cause of death by an infectious disease and its treatment is challenging …

Mycobacterium tuberculosis (Mtb) is able to persist in the body through months of multi‐drug
therapy. Mycobacteria possess a wide range of regulatory proteins, including the protein …