Awareness and current knowledge of Parkinson's disease: a neurodegenerative disorder

AU Khan, M Akram, M Daniyal… - International Journal of …, 2019 - Taylor & Francis
Context: Parkinson's disease (PD) is the second common progressive neurodegenerative
disease, distressing older men and is prevalent Worldwide. Objectives: This article is aimed …

Is cannabidiol the ideal drug to treat non-motor Parkinson's disease symptoms?

JAS Crippa, JEC Hallak, AW Zuardi… - European archives of …, 2019 - Springer
Parkinson's disease (PD) is a chronic neurodegenerative disorder characterized by motor
symptoms such as bradykinesia, rest tremor, postural disturbances, and rigidity. PD is also …

L‐DOPA for Parkinson's disease—a bittersweet pill

EL Lane - European Journal of Neuroscience, 2019 - Wiley Online Library
dihydroxy‐L‐phenylalanine (L‐DOPA) is the gold standard treatment for Parkinson's
disease. It has earned that title through its highly effective treatment of some of the motor …

Using wearables to assess bradykinesia and rigidity in patients with Parkinson's disease: a focused, narrative review of the literature

I Teshuva, I Hillel, E Gazit, N Giladi, A Mirelman… - Journal of Neural …, 2019 - Springer
The potential of using wearable technologies for the objective assessment of motor
symptoms in Parkinson's disease (PD) has gained prominence recently. Nonetheless …

Computational polymorph screening reveals late-appearing and poorly-soluble form of rotigotine

M Mortazavi, J Hoja, L Aerts, L Quéré… - Communications …, 2019 - nature.com
The active pharmaceutical ingredient rotigotine—a dopamine agonist for the treatment of
Parkinson's and restless leg diseases—was known to exist in only one polymorphic form …

Safety and tolerability of pharmacotherapies for Parkinson's disease in geriatric patients

M Klietz, S Greten, F Wegner, GU Höglinger - Drugs & Aging, 2019 - Springer
Parkinson's disease is a chronic neurodegenerative movement disorder affecting people
mainly beyond their 50s. Geriatric patients with Parkinson's disease experience a specific …

Should there be less emphasis on levodopa-induced dyskinesia in Parkinson's disease?

KR Chaudhuri, P Jenner, A Antonini - Movement Disorders: Official …, 2019 - europepmc.org
Should there be less emphasis on levodopa-induced dyskinesia in Parkinson's disease? -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

Can therapeutic strategies prevent and manage dyskinesia in Parkinson's disease? An update

V Leta, P Jenner, KR Chaudhuri… - Expert opinion on drug …, 2019 - Taylor & Francis
Introduction: Dyskinesia is a motor complication of Parkinson's disease (PD) characterized
by clinical heterogeneity and complex pathogenesis and associated with long-term …

Serum N-glycosylation in Parkinson's disease: a novel approach for potential alterations

C Váradi, K Nehéz, O Hornyák, B Viskolcz, J Bones - Molecules, 2019 - mdpi.com
In this study, we present the application of a novel capillary electrophoresis (CE) method in
combination with label-free quantitation and support vector machine-based feature selection …

The roles of galectin-3 and galectin-4 in the idiopatic Parkinson disease and its progression

T Cengiz, S Türkboyları, OS Gençler, Ö Anlar - Clinical neurology and …, 2019 - Elsevier
Abstract Objectives: Idiopathic Parkinson's Disease is a neurodegenerative disease caused
by the loss of cells that secrete dopamine in the basal ganglia. Galectins are multipotent …