[HTML][HTML] Autoimmune disease in women: endocrine transition and risk across the lifespan

MK Desai, RD Brinton - Frontiers in endocrinology, 2019 - frontiersin.org
Women have a higher incidence and prevalence of autoimmune diseases than men, and
85% or more patients of multiple autoimmune diseases are female. Women undergo …

Impact of sex hormones on immune function and multiple sclerosis development

MC Ysrraelit, J Correale - Immunology, 2019 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) affecting young people and leading to demyelination and neurodegeneration. The …

UK consensus on pregnancy in multiple sclerosis:'Association of British Neurologists' guidelines

R Dobson, P Dassan, M Roberts, G Giovannoni… - Practical …, 2019 - pn.bmj.com
Multiple sclerosis (MS) is more common in women than men and is most commonly
diagnosed in early adulthood; thus, many patients will not have completed their families at …

Pregnancy and family planning in multiple sclerosis

AM Langer-Gould - CONTINUUM: Lifelong Learning in Neurology, 2019 - journals.lww.com
Pregnancy and Family Planning in Multiple Sclerosis : CONTINUUM: Lifelong Learning in
Neurology Account Register Activate Subscription Help Subscribe American Academy of …

Post-natalizumab disease reactivation in multiple sclerosis: systematic review and meta-analysis

L Prosperini, RP Kinkel, AA Miravalle… - Therapeutic …, 2019 - journals.sagepub.com
Background: Natalizumab (NTZ) is sometimes discontinued in patients with multiple
sclerosis, mainly due to concerns about the risk of progressive multifocal …

The pregnancy pickle: evolved immune compensation due to pregnancy underlies sex differences in human diseases

H Natri, AR Garcia, KH Buetow, BC Trumble… - Trends in Genetics, 2019 - cell.com
We hypothesize that, ancestrally, sex-specific immune modulation evolved to facilitate
survival of the pregnant person in the presence of an invasive placenta and an …

Immunological basis for recurrent fetal loss and pregnancy complications

H Deshmukh, SS Way - Annual Review of Pathology …, 2019 - annualreviews.org
Pregnancy stimulates an elaborate assortment of dynamic changes, allowing intimate
approximation of genetically discordant maternal and fetal tissues. Although the cellular and …

[HTML][HTML] Therapeutic potential of extracellular vesicles for the treatment of nerve disorders

LR Galieva, V James, YO Mukhamedshina… - Frontiers in …, 2019 - frontiersin.org
The use of extracellular vesicles (EVs) as cell free therapy is a promising approach to
stimulate tissue regeneration including that of the nervous system. EVs transfer bioactive …

ERα signaling increased IL-17A production in Th17 cells by upregulating IL-23R expression, mitochondrial respiration, and proliferation

H Fuseini, JY Cephus, P Wu, JB Davis… - Frontiers in …, 2019 - frontiersin.org
Women have increased prevalence of Th17-mediated autoimmune diseases, including
lupus and multiple sclerosis, and severe asthma. While estradiol and progesterone …

What you need to know about AQP4, MOG, and NMOSD

S Prasad, J Chen - Seminars in Neurology, 2019 - thieme-connect.com
Neuromyelitis optica (NMO) is an antibody-mediated inflammatory disease of the central
nervous system with a predilection for the optic nerves, spinal cord, and certain brain …