DA Collier, C Monit, RK Gupta - Cell host & microbe, 2019 - cell.com
The rising prevalence of HIV drug resistance (HIVDR) could threaten gains made in combating the HIV epidemic and compromise the 90-90-90 target proposed by United …
S Spudich, KR Robertson, RJ Bosch… - The Journal of …, 2019 - Am Soc Clin Investig
BACKGROUND Persistence of HIV in sanctuary sites despite antiretroviral therapy (ART) presents a barrier to HIV remission and may affect neurocognitive function. We assessed …
Background Human immunodeficiency virus type 1 (HIV-1) populations are detected in cerebrospinal fluid (CSF) of some people on suppressive antiretroviral therapy (ART) …
I Pérez-Valero, R Ellis, R Heaton, R Deutsch… - Aids, 2019 - journals.lww.com
Background: During antiretroviral therapy, HIV RNA can be detected in cerebrospinal fluid (CSF) when it is undetectable in plasma, a condition termed 'CSF viral escape'. The aim of …
S Kodidela, K Gerth, S Haque, Y Gong, S Ismael… - Cells, 2019 - mdpi.com
The longevity of people with HIV/AIDS has been prolonged with the use of antiretroviral therapy (ART). The age-related complications, especially cognitive deficits, rise as HIV …
Suppression of plasma HIV RNA is most often attainable with effective antiretroviral therapy. Despite this, in some individuals, detection of HIV RNA remains evident in the cerebrospinal …
GMA Santos, I Locatelli, M Métral… - Open forum …, 2019 - academic.oup.com
Background Neurocognitive impairment (NCI) in people with human immunodeficiency virus (PWH) remains a concern despite potent antiretroviral therapy (ART). Higher central nervous …
S Spudich, J Peterson, D Fuchs, RW Price, M Gisslen - Aids, 2019 - journals.lww.com
Although treatment with antiretroviral therapy (ART) improves central nervous inflammation, limits viral replication detected in the cerebrospinal fluid, and prevents severe clinical …
SB Joseph, M Trunfio, LP Kincer, A Calcagno… - Aids, 2019 - journals.lww.com
Objective: To review the evidence that CSF (cerebrospinal fluid) escape populations are produced by viral reservoirs in the central nervous system (CNS). Design: CSF escape is a …