Adult cortical areas consist of specialized cell types and circuits that support unique higher- order cognitive functions. How this regional diversity develops from an initially uniform …
Spatial and molecular characteristics determine tissue function, yet high-resolution methods to capture both concurrently are lacking. Here, we developed high-definition spatial …
INTRODUCTION Blood is the predominant source for molecular analyses in humans, both in clinical and research settings, and is the target for many therapeutic strategies, emphasizing …
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical …
The recent availability of comprehensive, brain-wide gene expression atlases such as the Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …
The recent construction of brain-wide gene expression atlases, which measure the transcriptional activity of thousands of genes in multiple anatomical locations, has made it …
Schizophrenia has been conceived as a disorder of brain connectivity, but it is unclear how this network phenotype is related to the underlying genetics. We used morphometric …
S Pöyhönen, S Er, A Domanskyi… - Frontiers in physiology, 2019 - frontiersin.org
Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central nervous system and have been shown to play crucial roles in regulating both normal and …
The brain is an assembly of neuronal populations interconnected by structural pathways. Brain activity is expressed on and constrained by this substrate. Therefore, statistical …