[HTML][HTML] TreeCluster: Clustering biological sequences using phylogenetic trees

M Balaban, N Moshiri, U Mai, X Jia, S Mirarab - PloS one, 2019 - journals.plos.org
Clustering homologous sequences based on their similarity is a problem that appears in
many bioinformatics applications. The fact that sequences cluster is ultimately the result of …

Ethical issues in HIV phylogenetics and molecular epidemiology

SR Mehta, C Schairer, S Little - Current Opinion in HIV and AIDS, 2019 - journals.lww.com
HIV molecular epidemiology for research and public health pose significant ethical issues
that continue to evolve with improving technology, increased sampling and a changing legal …

Understanding disclosed and cryptic HIV transmission risk via genetic analysis: what are we missing and when does it matter?

M Ragonnet-Cronin, EB Hodcroft… - Current Opinion in HIV …, 2019 - journals.lww.com
Analysis of HIV genetic sequence can resolve viral transmission patterns between risk
groups at unprecedented scales and levels of detail. Future research should focus on …

[HTML][HTML] Diverse large HIV-1 non-subtype B clusters are spreading among men who have sex with men in Spain

E Delgado, S Benito, V Montero, MT Cuevas… - Frontiers in …, 2019 - frontiersin.org
In Western Europe, the HIV-1 epidemic among men who have sex with men (MSM) is
dominated by subtype B. However, recently, other genetic forms have been reported to …

Phylogenetic methods inconsistently predict the direction of HIV transmission among heterosexual pairs in the HPTN 052 cohort

R Rose, M Hall, AD Redd, S Lamers… - The Journal of …, 2019 - academic.oup.com
Background We evaluated use of phylogenetic methods to predict the direction of human
immunodeficiency virus (HIV) transmission. Methods For 33 pairs of HIV-infected patients …

Reconstruction of the genetic history and the current spread of HIV-1 subtype A in Germany

K Hanke, NR Faria, D Kühnert, KP Yousef… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT HIV-1 non-B infections have been increasing in Europe for several years. In
Germany, subtype A belongs to the most abundant non-B subtypes showing an increasing …

[HTML][HTML] Effectiveness of transmitted drug resistance testing before initiation of antiretroviral therapy in HIV-positive individuals

S Lodi, HF Günthard, J Gill, AN Phillips… - JAIDS Journal of …, 2019 - journals.lww.com
Background: For people living with HIV, major guidelines in high-income countries
recommend testing for transmitted drug resistance (TDR) to guide the choice of first-line …

Caution is needed in interpreting HIV transmission chains by ultradeep sequencing

E Todesco, M Wirden, R Calin, A Simon, S Sayon… - Aids, 2019 - journals.lww.com
Objectives: Molecular epidemiology is applied to various aspects of HIV transmission
analyses. With ultradeep sequencing (UDS), in-depth characterization of transmission …

Factors influencing HIV-1 phylogenetic clustering

DM Junqueira, Z Sibisi, E Wilkinson… - Current Opinion in HIV …, 2019 - journals.lww.com
Factors influencing HIV-1 phylogenetic clustering : Current Opinion in HIV and AIDS Factors
influencing HIV-1 phylogenetic clustering : Current Opinion in HIV and AIDS Log in or Register …

[HTML][HTML] Large benefits to youth-focused HIV treatment-as-prevention efforts in generalized heterosexual populations: An agent-based simulation model

JE Mittler, JT Murphy, SE Stansfield… - PLoS Computational …, 2019 - journals.plos.org
Predominantly heterosexual HIV-1 epidemics like those in sub-Saharan Africa continue to
have high HIV incidence in young people. We used a stochastic, agent-based model for age …