Host–transposon interactions: conflict, cooperation, and cooption

RL Cosby, NC Chang, C Feschotte - Genes & development, 2019 - genesdev.cshlp.org
Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …

Centromere repeats: hidden gems of the genome

G Hartley, RJ O'Neill - Genes, 2019 - mdpi.com
Satellite DNAs are now regarded as powerful and active contributors to genomic and
chromosomal evolution. Paired with mobile transposable elements, these repetitive …

Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease

OH Tam, LW Ostrow, M Gale Hammell - Mobile DNA, 2019 - Springer
Abstract Transposable Elements (TEs) are mobile genetic elements whose sequences
constitute nearly half of the human genome. Each TE copy can be present in hundreds to …

On the population dynamics of junk: a review on the population genomics of transposable elements

Y Bourgeois, S Boissinot - Genes, 2019 - mdpi.com
Transposable elements (TEs) play an important role in shaping genomic organization and
structure, and may cause dramatic changes in phenotypes. Despite the genetic load they …

Pedigree-based estimation of human mobile element retrotransposition rates

J Feusier, WS Watkins, J Thomas, A Farrell… - Genome …, 2019 - genome.cshlp.org
Germline mutation rates in humans have been estimated for a variety of mutation types,
including single-nucleotide and large structural variants. Here, we directly measure the …

Chromosome-scale assemblies reveal the structural evolution of African cichlid genomes

MA Conte, R Joshi, EC Moore, SP Nandamuri… - …, 2019 - academic.oup.com
Background African cichlid fishes are well known for their rapid radiations and are a model
system for studying evolutionary processes. Here we compare multiple, high-quality …

Short tandem repeat expansions and RNA-mediated pathogenesis in myotonic dystrophy

ŁJ Sznajder, MS Swanson - International Journal of Molecular Sciences, 2019 - mdpi.com
Short tandem repeat (STR) or microsatellite, expansions underlie more than 50 hereditary
neurological, neuromuscular and other diseases, including myotonic dystrophy types 1 …

Transposable elements contribute to fungal genes and impact fungal lifestyle

A Muszewska, K Steczkiewicz… - Scientific Reports, 2019 - nature.com
The last decade brought a still growing experimental evidence of mobilome impact on host's
gene expression. We systematically analysed genomic location of transposable elements …

Human endogenous retroviruses and type 1 diabetes

S Levet, B Charvet, A Bertin, A Deschaumes… - Current Diabetes …, 2019 - Springer
Abstract Purpose of the Review The aim of this review is to discuss recent data pointing at
an involvement of human endogenous retroviruses (HERVs) in type 1 diabetes (T1D) onset …

A virome-wide clonal integration analysis platform for discovering cancer viral etiology

X Chen, J Kost, A Sulovari, N Wong, WS Liang… - Genome …, 2019 - genome.cshlp.org
Oncoviral infection is responsible for 12%–15% of cancer in humans. Convergent evidence
from epidemiology, pathology, and oncology suggests that new viral etiologies for cancers …