Epigenetic alternations concern heritable yet reversible changes in histone or DNA
modifications that regulate gene activity beyond the underlying sequence. Epigenetic …

Artificial intelligence (AI)—the ability of a machine to perform cognitive tasks to achieve a
particular goal based on provided data—is revolutionizing and reshaping our health-care …

Cancer remains one of the leading lethal diseases worldwide. Identifying biomarkers of
cancers might provide insights into the strategies for the development of novel targeted anti …

Epigenetic patterns, such as DNA methylation, histone modifications, and non-coding RNAs,
can be both driver factors and characteristic features of certain malignancies. Aberrant DNA …

Cancer is a complex genetic and epigenetic-based disease that has developed an armada
of mechanisms to escape cell death. The deregulation of apoptosis and autophagy, which …

Background Optimal therapeutic strategies for hepatocellular carcinoma (HCC) patients are
still challenging due to the high recurrence rate after surgical resection and chemotherapy …

Introduction: Acetylation is a widely occurring post-translational modification (PTM) of
proteins that plays a crucial role in many cellular physiological and pathological processes …

Pediatric solid tumors have long been known to shed tumor cells, DNA, RNA, and proteins
into the blood. Recent technological advances have allowed for improved capture and …

Background Beta-carotene (BC) is a carotenoid which exerts anti-cancer effects in several
types of cancer, including colorectal cancer. Epigenetic modifications of genes, such as …

A level of epigenetic programming, encoded by complex sets of chemical marks on DNA
and histones, and by context-specific DNA, RNA, protein interactions, that all regulate the …