[HTML][HTML] Three hypomethylated genes were associated with poor overall survival in pancreatic cancer patients
H Chen, Y Kong, Q Yao, X Zhang, Y Fu, J Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is a highly malignant cancer with poor prognosis and high mortality.
Aberrant DNA methylation plays a critical role in the occurrence, progression and prognosis …
Aberrant DNA methylation plays a critical role in the occurrence, progression and prognosis …
[HTML][HTML] Lamin B1 in cancer and aging
BK Garvalov, S Muhammad, G Dobreva - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Importantly, depletion of lamin B1, EZH1 or EZH2 led to a similar induction of senescence
with establishment of senescence-like chromatin changes [6, 7]. These findings suggest that …
with establishment of senescence-like chromatin changes [6, 7]. These findings suggest that …
In silico analysis of human renin gene–gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing …
Three-dimensional chromatin architecture and gene–gene interactions impact gene
expression. We assembled this information, in silico, for the human renin gene (REN). We …
expression. We assembled this information, in silico, for the human renin gene (REN). We …
[PDF][PDF] “Escape” from oncogene induced senescence
A Angelopoulou - pergamos.lib.uoa.gr
The reversibility of senescence has been an issue highly disputable until recently, thus the
factors driving this event remain still elusive. Using a human epithelial model, we …
factors driving this event remain still elusive. Using a human epithelial model, we …
[PDF][PDF] Clinical Mass Spectrometry
EM Bux, V Solis-Mezarino, C Kuhm, BH Northoff… - researchgate.net
abstract Misregulated chromatin remodeling via erroneous histone acetylation has been
linked with multiple diseases including many age-associated maladies. Previous studies on …
linked with multiple diseases including many age-associated maladies. Previous studies on …