Changes of the coronary arteries and cardiac microvasculature with aging: Implications for translational research and clinical practice
F Piccirillo, M Carpenito, G Verolino, C Chello… - Mechanisms of ageing …, 2019 - Elsevier
Aging results in functional and structural changes in the cardiovascular system, translating
into a progressive increase of mechanical vessel stiffness, due to a combination of changes …
into a progressive increase of mechanical vessel stiffness, due to a combination of changes …
Phloretin and its methylglyoxal adduct: Implications against advanced glycation end products-induced inflammation in endothelial cells
Methylglyoxal (MGO), a cytotoxic factor, reacts irreversibly with the side chains of lysine,
cysteine, and arginine residues in proteins to form advanced glycation end products (AGEs) …
cysteine, and arginine residues in proteins to form advanced glycation end products (AGEs) …
Matrine alleviates AGEs-induced cardiac dysfunctions by attenuating calcium overload via reducing ryanodine receptor 2 activity
J Wang, Z Tang, Y Zhang, C Qiu, L Zhu, N Zhao… - European Journal of …, 2019 - Elsevier
Featured by heart dysfunction, the diabetic cardiomyopathy is causing mortality and
morbidity in type 2 diabetes mellitus patients. Matrine was considered as a cardioprotective …
morbidity in type 2 diabetes mellitus patients. Matrine was considered as a cardioprotective …
Post-translational modifications on glycated plasma fibrinogen: A physicochemical insight
Methylglyoxal (MGO) is a highly reactive α-oxoaldehyde. It reacts with basic amino acids of
the proteins to form advanced glycation end products (AGEs). Fibrinogen is a soluble multi …
the proteins to form advanced glycation end products (AGEs). Fibrinogen is a soluble multi …
Development and evaluation of novel ELISA for determination of urinary pentosidine
S Kashiwabara, H Hosoe, RI Ohno, R Nagai… - Journal of Nutritional …, 2019 - jstage.jst.go.jp
Pentosidine is the most well-characterized advanced glycation end product (AGE). It has
been measured by HPLC, although this approach cannot be adapted to analyze many …
been measured by HPLC, although this approach cannot be adapted to analyze many …