[HTML][HTML] Impacts of psychological stress on osteoporosis: clinical implications and treatment interactions

RR Kelly, LT McDonald, NR Jensen, SJ Sidles… - Frontiers in …, 2019 - frontiersin.org
The significant biochemical and physiological effects of psychological stress are beginning
to be recognized as exacerbating common diseases, including osteoporosis. This review …

Bench-to-bedside strategies for osteoporotic fracture: From osteoimmunology to mechanosensation

Y Xie, L Zhang, Q Xiong, Y Gao, W Ge, P Tang - Bone research, 2019 - nature.com
Osteoporosis is characterized by a decrease in bone mass and strength, rendering people
prone to osteoporotic fractures caused by low-energy forces. The primary treatment strategy …

Review of animal models of comorbidities in fracture‐healing research

M Haffner‐Luntzer, KD Hankenson… - Journal of …, 2019 - Wiley Online Library
There is clinical evidence that patient‐specific comorbidities like osteoporosis, concomitant
tissue injury, and ischemia may strongly interfere with bone regeneration. However …

Osteoporotic changes in the periodontium impair alveolar bone healing

M Arioka, X Zhang, Z Li, US Tulu, Y Liu… - Journal of dental …, 2019 - journals.sagepub.com
Osteoporosis is associated with decreased bone density and increased bone fragility, but
how this disease affects alveolar bone healing is not clear. The objective of this study was to …

Current progress on microrna‐based gene delivery in the treatment of osteoporosis and osteoporotic fracture

X Sun, Q Guo, W Wei, S Robertson… - International journal …, 2019 - Wiley Online Library
Emerging evidence demonstrates that microRNAs, as important endogenous
posttranscriptional regulators, are essential for bone remodeling and regeneration …

[PDF][PDF] Vibration treatment modulates macrophage polarisation and enhances early inflammatory response in oestrogen-deficient osteoporotic-fracture healing

SK Chow, YN Chim, J Wang, N Zhang, RM Wong… - Eur Cell …, 2019 - ecmjournal.org
Fracture healing is a well-orchestrated and coordinated process and begins with the
inflammatory stage involving the infiltration of immune cells and the release of cytokines …

The bidirectional interactions between inflammation and coagulation in fracture hematoma

Y Ma, Y Zhou, F Wu, W Ji, J Zhang… - Tissue Engineering Part …, 2019 - liebertpub.com
Research regarding the intimate relationship between inflammation and coagulation in
fracture hematoma has attracted increasing attention recently. However, the interaction of …

Mechanisms underlying normal fracture healing and risk factors for delayed healing

C Cheng, D Shoback - Current Osteoporosis Reports, 2019 - Springer
Abstract Purpose of Review Substantial advances have been made in understanding the
biological basis of fracture healing. Yet, it is unclear whether the presence of osteoporosis or …

[HTML][HTML] Animal models in orthopedic research: the proper animal model to answer fundamental questions on bone healing depending on pathology and implant …

NG Sommer, D Hahn, B Okutan, R Marek… - Animal models in …, 2019 - intechopen.com
Different species vary in bone metabolism, especially in modeling and remodeling of the
bone. Human-related diseases with severe outcomes on bone, such as osteoporosis or …

[PDF][PDF] A metaphyseal fracture rat model for mechanistic studies of osteoporotic bone healing

RM Wong, U Thormann, MH Choy, YN Chim… - Eur Cell …, 2019 - researchgate.net
Most osteoporotic fractures occur at metaphyseal regions of long bones. The present study
proposed a clinically relevant animal model that satisfied: i) induction of osteoporosis, ii) …