The overall structure and architecture of the extracellular matrix undergo dramatic alterations
in composition, form, and functionality over time. The stochasticity begins during …

The extracellular matrix is a network of secreted macromolecules that provides a
harmonious meshwork for the growth and homeostatic development of organisms. It …

The immunoreceptor tyrosine-based inhibition motif (ITIM)-containing receptor G6b-B is
critical for platelet production and activation. Loss of G6b-B results in severe …

A growing body of research demonstrates modulation of autophagy by a variety of matrix
constituents, including decorin, endorepellin, and endostatin. These matrix proteins are both …

Platelet activation is tightly regulated by inhibitory mechanisms that limit platelet
accumulation at sites of vascular injury. This chapter covers the most well-established …

Decorin is a multi-faceted class I small, leucine-rich proteoglycan found ubiquitously in the
extracellular matrix. While originally identified as a regulator of collagen fibrillogenesis …