Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …

Cystic fibrosis (CF) lung disease is characterized by early and persistent mucus
accumulation and neutrophilic inflammation in the distal airways. Identification of the factors …

ABSTRACT Transmembrane member 16A (TMEM16A) is the Ca2+‐activated chloride
channel in airways and intestine. It has been associated with goblet cell metaplasia, as …

Rationale: The goal was to connect elements of idiopathic pulmonary fibrosis (IPF)
pathogenesis, including chronic endoplasmic reticulum stress in respiratory epithelia …

Goblet cell metaplasia, a disabling hallmark of chronic lung disease, lacks curative
treatments at present. To identify novel therapeutic targets for goblet cell metaplasia, we …

Goblet cell metaplasia and mucus hypersecretion are observed in many pulmonary
diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic …

It is widely accepted that inflammasomes protect the host from microbial pathogens by
inducing inflammatory responses through caspase-1 activation. Here, we show that the …

Mucin-secreting goblet cell metaplasia and hyperplasia (GCMH) is a common pathological
phenotype in many human respiratory diseases, including asthma, chronic obstructive …

Abstract Ethnopharmacological relevance Srolo Bzhtang (SBT), a traditional Tibetan
medicine formula, was composed of three herbs, Solms-Laubachia eurycarpa, Bergenia …

Abstract E74‐like factor 5 (ELF5) and ETS‐homologous factor (EHF) are epithelial selective
ETS family transcription factors (TFs) encoded by genes at chr11p13, a region associated …