The regulatory role of non-coding RNAs on programmed cell death four in inflammation and cancer

M Zhao, N Zhu, F Hao, Y Song, Z Wang, Y Ni… - Frontiers in …, 2019 - frontiersin.org
Programmed cell death 4 (PDCD4) is a tumor suppressor gene implicated in many cellular
functions, including transcription, translation, apoptosis, and the modulation of different …

The mechanisms and clinical significance of PDCD4 in colorectal cancer

J Long, Y Yin, H Guo, S Li, Y Sun, C Zeng, W Zhu - Gene, 2019 - Elsevier
In recent years, the incidence and mortality of colorectal cancer (CRC) have been on a
global upward trend. There is an urgent need for effective tools to prevent and treat CRC …

[HTML][HTML] MiR-181b-5p modulates chemosensitivity of glioma cells to temozolomide by targeting Bcl-2

X Zhang, J Yu, C Zhao, H Ren, Z Yuan, B Zhang… - Biomedicine & …, 2019 - Elsevier
Chemotherapy is the main postsurgical and adjuvant therapy for glioma, and intrinsic or
acquired temozolomide (TMZ) resistance may result in poor prognosis. The miR-181 family …

Altered expression of miR-181 affects cell fate and targets drug resistance-related mechanisms

C Braicu, D Gulei, L Raduly, A Harangus… - Molecular aspects of …, 2019 - Elsevier
MicroRNAs (miRNAs) are non-coding transcripts which regulate genetic and epigenetic
events by interfering with mRNA translation. miRNAs are involved in regulation of cell fate …

miR‐129‐5p and‐3p co‐target WWP1 to suppress gastric cancer proliferation and migration

L Ma, X Chen, C Li, R Cheng, Z Gao… - Journal of Cellular …, 2019 - Wiley Online Library
Gastric cancer (GC) is a worldwide health problem. Uncovering the underlining molecular
mechanisms of GC is of vital significance. Here, we identified a novel oncogene WW domain …

[HTML][HTML] MicroRNA-181b blocks gensenoside Rg3-mediated tumor suppression of gallbladder carcinoma by promoting autophagy flux via CREBRF/CREB3 pathway

K Wu, J Huang, T Xu, Z Ye, F Jin, N Li… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Background: Gallbladder cancer (GBC) is the seventh most common gastrointestinal cancer.
Suppression of autophagy contributes to cell death of gallbladder cancer. Gensenoside Rg3 …

Differentially expressed microRNAs in MIA PaCa-2 and PANC-1 pancreas ductal adenocarcinoma cell lines are involved in cancer stem cell regulation

Y Shen, K Pu, K Zheng, X Ma, J Qin, L Jiang… - International journal of …, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, and thus
better understanding of its molecular pathology is crucial for us to devise more effective …

Downregulated adhesion-associated microRNAs as prognostic predictors in childhood osteosarcoma

LEA Delsin, GM Roberto, PF Fedatto, EE Engel… - Pathology & Oncology …, 2019 - Springer
Abstract miRNAs have been identified as key regulators of almost all cellular processes,
therefore, their dysregulation is involved with several diseases, including cancer. miRNAs …

Programmed cell death factor 4 enhances the chemosensitivity of colorectal cancer cells to Taxol

D Wang, Q Hou, L Zhao, J Gao, Y Xiao… - Oncology …, 2019 - spandidos-publications.com
Drug resistance and disease relapse are still challenging problems in the chemotherapy of
colorectal cancer (CRC). Programmed cell death factor 4 (PDCD4) has previously been …