In recent years, the vascular endothelium has gained attention as a key player in the
initiation and development of pregnancy disorders. Endothelium acts as an endocrine organ …

Inflammation is often equated to the physiological response to injury or infection.
Inflammatory responses defined by cytokine storms control cellular mechanisms that can …

Background In utero exposure to obesity is consistently associated with increased risk of
metabolic disease, obesity and cardiovascular dysfunction in later life despite the …

Fetal development is modulated by maternal nutrition during pregnancy. The dietary intake
of linoleic acid (LA), an essential dietary n-6 polyunsaturated fatty acid (PUFA), has …

Background Epigenetics can contribute to lipid disorders in obesity. The DNA methylation
pattern can be the cause or consequence of high blood lipids. The aim of the study was to …

Maternal overweight in pregnancy alters the metabolic environment and generates chronic
low-grade inflammation. This affects fetal development and programs the offspring's health …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic
threat with more than 11.8 million confirmed cases and more than 0.5 million deaths as of 3 …

Metabolic disorders of the mother adversely affect early embryo development, causing
changes in maternal metabolism and consequent alterations in the embryo environment in …

Simple Summary Obesity increases the risk of problems during pregnancy, potentially due to
inappropriate activation of the immune system. We predicted that, because of this immune …

Background: The prevalence of obesity has increased globally and reached pandemic
levels. Obesity is associated with increased risks of complications during conception …