Oncogenic miRNAs and target therapies in colorectal cancer

A Saberinia, A Alinezhad, F Jafari, S Soltany… - Clinica Chimica …, 2020 - Elsevier
OncomiRNAs involved in human colorectal cancer (CRC) are capable of suppressing the
expression of their targets via cleavage or translational arrest. Therefore, an improved …

Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer

MG Costales, H Aikawa, Y Li… - Proceedings of the …, 2020 - National Acad Sciences
As the area of small molecules interacting with RNA advances, general routes to provide
bioactive compounds are needed as ligands can bind RNA avidly to sites that will not affect …

[HTML][HTML] Integrative systematic review meta-analysis and bioinformatics identifies MicroRNA-21 and its target genes as biomarkers for colorectal adenocarcinoma

NS Sharif-Askari, FS Sharif-Askari, SY Guraya… - International Journal of …, 2020 - Elsevier
Background Advanced colorectal has poor survival and are difficult to treat. Therefore, there
is an urgent need for biomarkers to diagnose this cancer at earlier manageable stages …

Tumor tissue MIR92a and plasma MIRs21 and 29a as predictive biomarkers associated with clinicopathological features and surgical resection in a prospective study …

M Fukada, N Matsuhashi, T Takahashi… - Journal of Clinical …, 2020 - mdpi.com
Cancer-related microRNAs (miRNAs) are emerging as non-invasive biomarkers for
colorectal cancer (CRC). This study aimed to analyze the correlation between the levels of …

Roles of microRNAs as non-invasive biomarker and therapeutic target in colorectal cancer.

TMH Wan, DN Iyer, L Ng - 2020 - digitum.um.es
MicroRNAs are endogenous, short non-coding RNA molecules that function as critical
regulators of various biological processes. There is a strong functional evidence linking the …

Computational and experimental tools of miRNAs in cancer

E Çakmak - 2020 - openaccess.ahievran.edu.tr
MicroRNAs (miRNAs) are short non-protein coding and single-stranded small RNA
molecules with a critical role in the regulation of gene expression. These molecules are …

Expressão de micro-RNAs associados a invasão tumoral e prognóstico em carcinoma de células escamosas de cavidade oral

M Júnior, G Mendes - teses.usp.br
Introdução: O carcinoma de células escamosas da cavidade oral é uma doença de alta
incidência e prognóstico ruim. Dentre os principais fatores prognósticos estão a presença …