[HTML][HTML] Interrelation between ROS and Ca2+ in aging and age-related diseases

CT Madreiter-Sokolowski, C Thomas, M Ristow - Redox biology, 2020 - Elsevier
Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …

Neurodegenerative diseases–is metabolic deficiency the root cause?

VR Muddapu, SAP Dharshini… - Frontiers in …, 2020 - frontiersin.org
Neurodegenerative diseases, including Alzheimer, Parkinson, Huntington, and amyotrophic
lateral sclerosis, are a prominent class of neurological diseases currently without a cure …

[HTML][HTML] Oxidative stress in cognitive and epigenetic aging: a retrospective glance

A Kandlur, K Satyamoorthy… - Frontiers in Molecular …, 2020 - frontiersin.org
Brain aging is the critical and common factor among several neurodegenerative disorders
and dementia. Cellular, biochemical and molecular studies have shown intimate links …

[HTML][HTML] Effects of the probiotic formulation SLAB51 in in vitro and in vivo Parkinson's disease models

V Castelli, M d'Angelo, F Lombardi, M Alfonsetti… - Aging (albany …, 2020 - ncbi.nlm.nih.gov
Parkinson is a common neurodegenerative disorder, characterized by motor and non-motor
symptoms, including abnormalities in the gut function, which may appear before the motor …

Neuroprotective role of polyphenols against oxidative stress-mediated neurodegeneration

MS Uddin, A Al Mamun, MT Kabir, J Ahmad… - European journal of …, 2020 - Elsevier
Neurodegenerative diseases (NDs) are characterized by disorders with progressive
deterioration of the structure and/or function of neurons. Genetic mutations can lead to many …

Neuroprotective potentials of marine algae and their bioactive metabolites: Pharmacological insights and therapeutic advances

MA Hannan, R Dash, MN Haque, M Mohibbullah… - Marine drugs, 2020 - mdpi.com
Beyond their significant contribution to the dietary and industrial supplies, marine algae are
considered to be a potential source of some unique metabolites with diverse health benefits …

MicroRNAs dysregulation and mitochondrial dysfunction in neurodegenerative diseases

M Catanesi, M d'Angelo, MG Tupone… - International Journal of …, 2020 - mdpi.com
Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …

The aging brain: Impact of heavy metal neurotoxicity

OM Ijomone, CW Ifenatuoha, OM Aluko… - Critical reviews in …, 2020 - Taylor & Francis
The aging process is accompanied by critical changes in cellular and molecular functions,
which upset the homeostatic balance in the central nervous system. Accumulation of metals …

Insights into the effects of mesenchymal stem cell-derived secretome in Parkinson's disease

M d'Angelo, A Cimini, V Castelli - International Journal of Molecular …, 2020 - mdpi.com
Mesenchymal stem cell (MSC)-derived secretome demonstrated therapeutic effects like
those reported after MSCs transplantation. MSC-derived secretome may avoid various side …

Role of sirtuins in modulating neurodegeneration of the enteric nervous system and central nervous system

P Chandramowlishwaran, A Vijay, D Abraham… - Frontiers in …, 2020 - frontiersin.org
Neurodegeneration of the central and enteric nervous systems is a common feature of aging
and aging-related diseases, and is accelerated in individuals with metabolic dysfunction …