Psychosocial stress and epigenetic aging
H Palma-Gudiel, L Fañanás, S Horvath… - International review of …, 2020 - Elsevier
Aging is the single most important risk factor for diseases that are currently the leading
causes of morbidity and mortality. However, there is considerable inter-individual variability …
causes of morbidity and mortality. However, there is considerable inter-individual variability …
[HTML][HTML] Epigenetics underlying susceptibility and resilience relating to daily life stress, work stress, and socioeconomic status
MG Gottschalk, K Domschke, MA Schiele - Frontiers in psychiatry, 2020 - frontiersin.org
Susceptibility and resilience to mental disorders result from a complex choreography of
gene–environment interactions with epigenetics at the intersection of external psychological …
gene–environment interactions with epigenetics at the intersection of external psychological …
Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children
Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …
turn has been shown to predict numerous physical and mental health problems. In recent …
Determinants of accelerated metabolomic and epigenetic aging in a UK cohort
O Robinson, M Chadeau Hyam, I Karaman… - Aging cell, 2020 - Wiley Online Library
Markers of biological aging have potential utility in primary care and public health. We
developed a model of age based on untargeted metabolic profiling across multiple …
developed a model of age based on untargeted metabolic profiling across multiple …
Special report: the biology of inequalities in health: the lifepath consortium
Funded by the European Commission Horizon 2020 programme, the Lifepath research
consortium aimed to investigate the effects of socioeconomic inequalities on the biology of …
consortium aimed to investigate the effects of socioeconomic inequalities on the biology of …
Association of neighborhood disadvantage in childhood with DNA methylation in young adulthood
Importance DNA methylation has been proposed as an epigenetic mechanism by which the
childhood neighborhood environment may have implications for the genome that …
childhood neighborhood environment may have implications for the genome that …
Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood
Our early-life environment has a profound influence on developing organs that impacts
metabolic function and determines disease susceptibility across the life-course. Using a rat …
metabolic function and determines disease susceptibility across the life-course. Using a rat …
Association of parental socioeconomic status and newborn telomere length
Importance Low socioeconomic status is associated with higher all-cause mortality and risks
for aging-related diseases. Biological aging is a potential process underlying health …
for aging-related diseases. Biological aging is a potential process underlying health …
Health inequalities: Embodied evidence across biological layers
Rationale Socioeconomic disparities have been documented in major non-communicable
diseases and in their risk factors, such as obesity, hypertension, diabetes, smoking, physical …
diseases and in their risk factors, such as obesity, hypertension, diabetes, smoking, physical …
Epigenetic clocks may come out of rhythm—implications for the estimation of chronological age in forensic casework
BE Koop, A Reckert, J Becker, Y Han… - International Journal of …, 2020 - Springer
There is a growing perception that DNA methylation may be influenced by exogenous and
endogenous parameters. Knowledge of these factors is of great relevance for the …
endogenous parameters. Knowledge of these factors is of great relevance for the …