Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and a leading
cause of cancer-related deaths worldwide. Ninety percent of HCC cases arise from cirrhosis …

Malignant liver tumours include a wide range of primary and secondary tumours. Although
surgery remains the mainstay of curative treatment, modern therapies integrate a variety of …

BACKGROUND Lenvatinib has become an indispensable part of treatment regimens for
patients with advanced hepatocellular carcinoma (aHCC). Several recent real-world studies …

Advanced hepatocellular carcinoma is a prevalent and potentially aggressive disease. For
more than a decade, treatment with sorafenib has been the only approved therapeutic …

Stem cells or their closely related committed progenitor cells are the likely founder cells of
most neoplasms. In the continually renewing and hierarchically organized epithelia of the …

Objective: To investigate the function of discoidin domain receptor 1 (DDR1) in
hepatocellular carcinoma (HCC) and to further clarify the underlying mechanism. Results …

Prediction of hepatocellular carcinoma (HCC) risk becomes increasingly important with
recently emerging HCC-predisposing conditions, namely non-alcoholic fatty liver disease …

Precise hepatocellular carcinoma (HCC) risk prediction will play increasingly important roles
with the contemporary HCC etiologies, that is, non‐alcoholic fatty liver disease and resolved …

Safe, efficient and cancer cell targeted delivery of CRISPR/Cas9 is important to increase the
effectiveness of available cancer treatments. Although cancer derived exosomes offer …

Background: The tumorigenesis and development of hepatocellular carcinoma (HCC) is a
process involving multiple factors. The COMMDs family proteins were reported to play …