The gut microbiota and inflammation: an overview

Z Al Bander, MD Nitert, A Mousa… - International journal of …, 2020 - mdpi.com
The gut microbiota encompasses a diverse community of bacteria that carry out various
functions influencing the overall health of the host. These comprise nutrient metabolism …

The firmicutes/bacteroidetes ratio: a relevant marker of gut dysbiosis in obese patients?

F Magne, M Gotteland, L Gauthier, A Zazueta, S Pesoa… - Nutrients, 2020 - mdpi.com
The gut microbiota is emerging as a promising target for the management or prevention of
inflammatory and metabolic disorders in humans. Many of the current research efforts are …

The controversial role of human gut lachnospiraceae

M Vacca, G Celano, FM Calabrese, P Portincasa… - Microorganisms, 2020 - mdpi.com
The complex polymicrobial composition of human gut microbiota plays a key role in health
and disease. Lachnospiraceae belong to the core of gut microbiota, colonizing the intestinal …

Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

J Aron-Wisnewsky, C Vigliotti, J Witjes, P Le… - Nature Reviews …, 2020 - nature.com
Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …

Gut microbiota and dysbiosis in Alzheimer's disease: implications for pathogenesis and treatment

S Liu, J Gao, M Zhu, K Liu, HL Zhang - Molecular neurobiology, 2020 - Springer
Understanding how gut flora influences gut-brain communications has been the subject of
significant research over the past decade. The broadening of the term “microbiota-gut-brain …

Host–microbiota interactions in immune-mediated diseases

WE Ruff, TM Greiling, MA Kriegel - Nature Reviews Microbiology, 2020 - nature.com
Host–microbiota interactions are fundamental for the development of the immune system.
Drastic changes in modern environments and lifestyles have led to an imbalance of this …

Role of dietary nutrients in the modulation of gut microbiota: a narrative review

Q Yang, Q Liang, B Balakrishnan, DP Belobrajdic… - Nutrients, 2020 - mdpi.com
Understanding how dietary nutrients modulate the gut microbiome is of great interest for the
development of food products and eating patterns for combatting the global burden of non …

Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor

SA Scott, J Fu, PV Chang - Proceedings of the National …, 2020 - National Acad Sciences
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are
associated with dysbiosis of the gut microbiome. Emerging evidence suggests that small …

Diversification of host bile acids by members of the gut microbiota

JA Winston, CM Theriot - Gut microbes, 2020 - Taylor & Francis
Bile acid biotransformation is a collaborative effort by the host and the gut microbiome. Host
hepatocytes synthesize primary bile acids from cholesterol. Once these host-derived primary …

Tara Oceans: towards global ocean ecosystems biology

S Sunagawa, SG Acinas, P Bork, C Bowler… - Nature Reviews …, 2020 - nature.com
A planetary-scale understanding of the ocean ecosystem, particularly in light of climate
change, is crucial. Here, we review the work of Tara Oceans, an international …