Thyroid nodules: diagnostic evaluation based on thyroid cancer risk assessment

NS Ospina, NM Iñiguez-Ariza, MR Castro - bmj, 2020 - bmj.com
Thyroid nodules are extremely common and can be detected by sensitive imaging in more
than 60% of the general population. They are often identified in patients without symptoms …

A systematic literature review of whole exome and genome sequencing population studies of genetic susceptibility to cancer

M Rotunno, R Barajas, M Clyne, E Hoover… - … Biomarkers & Prevention, 2020 - AACR
The application of next-generation sequencing (NGS) technologies in cancer research has
accelerated the discovery of somatic mutations; however, progress in the identification of …

Germline mutations in familial papillary thyroid cancer

M Sarquis, DC Moraes, L Bastos-Rodrigues… - Endocrine …, 2020 - Springer
Thyroid cancer, predominantly of papillary histology (PTC), is a common cancer mostly
diagnosed sporadically. Hereditary PTC is encountered in~ 5% of cases and may present at …

Genetic mutations and variants in the susceptibility of familial non-medullary thyroid cancer

FY Miasaki, CS Fuziwara, GA Carvalho, ET Kimura - Genes, 2020 - mdpi.com
Thyroid cancer is the most frequent endocrine malignancy with the majority of cases derived
from thyroid follicular cells and caused by sporadic mutations. However, when at least two or …

An update on familial nonmedullary thyroid cancer

SA Ammar, WM Alobuia, E Kebebew - Endocrine, 2020 - Springer
Familial nonmedullary thyroid cancer (FNMTC) constitutes 3–9% of all thyroid cancer cases.
FNMTC is divided into two groups: syndromic and nonsyndromic. Nonsyndromic FNMTC is …

Protease activated receptors (PAR)‐1 and‐2 mediate cellular effects of factor VII activating protease (FSAP).

K Byskov, SM le Gall, B Thiede, E Camerer… - The FASEB …, 2020 - duo.uio.no
Factor VII activating protease (FSAP) is a circulating serine protease implicated in
thrombosis, atherosclerosis, stroke, and cancer. Using an overexpression strategy, we have …

Lack of Mutations in POT1 Gene in Selected Families with Familial Non-Medullary Thyroid Cancer

A Orois, C Badenas, JL Reverter, V López… - Hormones and …, 2020 - Springer
To date, the genes involved in familial non-medullary thyroid cancer (FNMTC) remain poorly
understood, with the exception of syndromic cases of FNMTC. It has been proposed that …

Familial aggregation and heritability of nonmedullary thyroid cancer in an Asian population: a nationwide cohort study

HT Lin, FC Liu, SF Lin, CF Kuo… - The Journal of Clinical …, 2020 - academic.oup.com
Purpose The purpose of this work is to assess the extent of familial aggregation of
nonmedullary thyroid cancer (NMTC) and the relative risks (RRs) of chronic thyroid diseases …

[HTML][HTML] Comparative eye and liver differentially expressed genes reveal monochromatic vision and cancer resistance in the shortfin mako shark (Isurus oxyrinchus)

RR Domingues, VA Mastrochirico-Filho, NJ Mendes… - Genomics, 2020 - Elsevier
The shortfin mako, Isurus oxyrinchus is an oceanic pelagic shark found worldwide in tropical
and subtropical waters. However, the understanding of its biology at molecular level is still …

[HTML][HTML] Cellular effects of factor VII activating protease (FSAP)

K Byskov, M Etscheid, SM Kanse - Thrombosis Research, 2020 - Elsevier
Factor VII activating protease (FSAP) is a circulating serine protease of broad specificity that
is likely to be involved in many pathophysiological processes. The activation of the …