[PDF][PDF] A replication-competent vesicular stomatitis virus for studies of SARS-CoV-2 spike-mediated cell entry and its inhibition

ME Dieterle, D Haslwanter, RH Bortz… - Cell host & …, 2020 - cell.com
There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid
SARS-CoV-2 countermeasure development is contingent on the availability of robust …

[HTML][HTML] Orthohantavirus pathogenesis and cell tropism

D Noack, M Goeijenbier, CBEM Reusken… - Frontiers in cellular …, 2020 - frontiersin.org
Orthohantaviruses are zoonotic viruses that are naturally maintained by persistent infection
in specific reservoir species. Although these viruses mainly circulate among rodents …

Humoral immunity to hantavirus infection

TB Engdahl, JE Crowe Jr - MSphere, 2020 - Am Soc Microbiol
Hantaviruses are zoonotic pathogens found in parts of Europe, Asia, South America, and
North America, which can cause renal and respiratory failure with fatality rates up to 40 …

Neutralizing monoclonal antibodies against the Gn and the Gc of the Andes virus glycoprotein spike complex protect from virus challenge in a preclinical hamster …

J Duehr, M McMahon, B Williamson, F Amanat… - MBio, 2020 - Am Soc Microbiol
Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS)
and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case …

Advances in high-throughput methods for the identification of virus receptors

SV Barrass, SJ Butcher - Medical microbiology and immunology, 2020 - Springer
Viruses have evolved many mechanisms to invade host cells and establish successful
infections. The interaction between viral attachment proteins and host cell receptors is the …

[HTML][HTML] T-cell immunoglobulin and mucin (TIM) contributes to the infection of human airway epithelial cells by pseudotype viruses containing Hantaan virus …

J Mayor, G Torriani, S Rothenberger, O Engler - Virology, 2020 - Elsevier
Hantaviruses are rodent-borne hemorrhagic fever viruses leading to serious diseases. Viral
attachment and entry represent the first steps in virus transmission and are promising targets …

Isolation and characterization of new Puumala orthohantavirus strains from Germany

F Binder, S Reiche, G Roman-Sosa, M Saathoff, R Ryll… - Virus Genes, 2020 - Springer
Orthohantaviruses are re-emerging rodent-borne pathogens distributed all over the world.
Here, we report the isolation of a Puumala orthohantavirus (PUUV) strain from bank voles …

Generation and characterization of an Il2rg knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients

R Li, B Ying, Y Liu, JF Spencer, J Miao… - Disease models & …, 2020 - journals.biologists.com
Model animals are indispensable for the study of human diseases, and in general, of
complex biological processes. The Syrian hamster is an important model animal for …

A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover

H Moreno, A Rastrojo, R Pryce, C Fedeli… - PLoS neglected …, 2020 - journals.plos.org
A detailed understanding of the mechanisms underlying the capacity of a virus to break the
species barrier is crucial for pathogen surveillance and control. New World (NW) …

[HTML][HTML] Meeting report: Eleventh international conference on hantaviruses

J Clement, C Ahlm, T Avšič-Županc, J Botten… - Antiviral Research, 2020 - Elsevier
Abstract The 2019 11th International Conference on Hantaviruses (ICH 2019) was
organized by the International Society for Hantaviruses (ISH), and held on September 1–4 …