Abstract The Dystrophin Glycoprotein Complex (DGC) is a large multi-protein complex that
links cytoskeleton actin to the extracellular matrix. This complex is critical in maintaining the …

Muscular dystrophies are a group of more than 160 different human neuromuscular
disorders characterized by a progressive deterioration of muscle mass and strength. The …

Duchenne muscular dystrophy is a severe pediatric neuromuscular disorder caused by the
lack of dystrophin. Identification of biomarkers is needed to support and accelerate drug …

Dystrophin-deficient cardiomyopathy (DDC) is currently the leading cause of death in
patients with dystrophinopathies. Targeting myocardial fibrosis (MF) has become a major …

Duchenne muscular dystrophy (DMD) is an X-linked disorder caused by the lack of
functional dystrophin protein. In muscular dystrophy preclinical research, it is pertinent to …

The ultimate goal of precision disease modeling is to artificially recreate the disease of
affected people in a highly controllable and adaptable external environment. This field has …

Récemment, notre laboratoire a décrit plusieurs patients atteints d'une forme sévère et
progressive de dystonie présentant des mutations de novo dans le gène du récepteur bêta …