Sepsis is a life-threatening organ dysfunction that results from the body's response to
infection. It requires prompt recognition, appropriate antibiotics, careful hemodynamic …

Inflammation is a key feature in the pathogenesis of sepsis and acute respiratory distress
syndrome (ARDS). Sepsis and ARDS continue to be associated with high mortality. A key …

Background Fluid and vasopressor management in septic shock remains controversial. In
this randomized controlled trial, we evaluated the efficacy of dynamic measures (stroke …

Importance Use of empirical broad-spectrum antibiotics for pneumonia has increased owing
to concern for resistant organisms, including methicillin-resistantStaphylococcus aureus …

Objective Administration of diuretics has been shown to assist fluid management and
improve clinical outcomes in the critically ill post-shock resolution. Current guidelines have …

Background Conducting research in critically-ill patient populations is challenging, and most
randomized trials of critically-ill patients have not achieved pre-specified statistical …

BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …

Purpose Measurement of central venous pressure (CVP) can be a useful clinical tool.
However, the formal utility of CVP measurement in preventing mortality in septic patients has …

Background Sepsis is the leading cause of intensive care unit (ICU) admission. The purpose
of this study was to explore the prognostic value of the Sequential Organ Failure …

Background No recommendation exists about the timing and setting for tracheal intubation
and mechanical ventilation in septic shock. Patients and methods This prospective …