Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications, and other age-related diseases

CG Schalkwijk, CDA Stehouwer - Physiological reviews, 2020 - journals.physiology.org
The formation and accumulation of methylglyoxal (MGO), a highly reactive dicarbonyl
compound, has been implicated in the pathogenesis of type 2 diabetes, vascular …

Methylglyoxal induces nuclear accumulation of p53 and γH2AX in normal and cancer cells

A Veß, T Hollemann - bioRxiv, 2020 - biorxiv.org
The formation and accumulation of methylglyoxal (MGO) is associated with age-related
diseases such as diabetes, cancer and neurodegenerative disorders. MGO is the major …

Effect of nutritional factors (with a focus on vitamin D) on disease progression in non-alcoholic fatty liver disease (NAFLD): mechanistic and public health approaches.

OA Akinyemi - 2020 - openresearch.surrey.ac.uk
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease affecting up to one-third
of the adult population in western countries. NAFLD is characterised by increased lipid …