Atherosclerosis is one of the most common diseases of the cardiovascular system that leads
to the development of life-threatening conditions, such as heart attack and stroke …

The use of genomic information to better understand and prevent common complex
diseases has been an ongoing goal of genetic research. Over the past few years, research …

Objectives To investigate associations between a high genetic disease risk and disease
severity in patients with systemic lupus erythematosus (SLE). Methods Patients with SLE (n …

Using three European and two Chinese genome-wide association studies (GWAS), we
investigated the performance of genetic risk scores (GRSs) for predicting the susceptibility …

Background Telomere length is an important indicator of tumor progression and survival for
cancer patients. Previous work investigated the associations between genetically predicted …

Obesity is a multifactorial condition arising from the interaction between genetic and lifestyle
factors. We aimed to assess the impact of lifestyle and genetic factors on obesity-related …

Importance Obesity is a major determinant of disease burden worldwide. Polygenic risk
scores (PRSs) have been posited as key predictors of obesity. How a PRS can be translated …

Studies in Asian Indians have examined the association of metabolic traits with vitamin D
status. However, findings have been quite inconsistent. Hence, we aimed to explore the …

Aim To conduct a comprehensive review of studies of glycaemic deterioration in type 2
diabetes and identify the major factors influencing progression. Methods We conducted a …

Single-nucleotide polymorphisms based genetic risk score in the prediction of pancreatic
cancer risk - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …